P
US9828361B2ActiveUtilityPatentIndex 92

Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

Assignee: CELGENE CORPPriority: Feb 11, 2010Filed: Feb 10, 2016Granted: Nov 28, 2017
Est. expiryFeb 11, 2030(~3.6 yrs left)· nominal 20-yr term from priority
Inventors:MAN HON-WAHCHEN ROGER SHEN-CHUMULLER GEORGE WRUCHELMAN ALEXANDER LKHALIL EHAB MZHANG WEIHONG
A61P 43/00A61P 37/02A61P 9/14A61P 7/06A61P 9/10A61P 39/02A61P 37/04A61P 9/00A61P 7/00A61P 31/18A61P 25/00A61P 25/20A61P 25/04A61P 31/00A61P 27/02A61P 35/00A61P 29/00A61P 33/00A61P 17/00A61P 19/02A61P 11/00A61P 21/00C07D 417/14C07D 409/14C07D 487/04C07D 401/12C07D 407/12C07D 493/04C07D 471/04C07D 491/107C07D 401/04C07D 495/04C07D 413/14C07D 407/14C07D 401/14A61K 31/4412C07D 498/08C07D 405/14A61P 7/04
92
PatentIndex Score
12
Cited by
66
References
10
Claims

Abstract

Provided are 4′-arylmethoxy isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A compound of the formula: 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable salt or stereoisomer thereof. 
     
     
       2. The compound of  claim 1 , which is 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable salt thereof. 
     
     
       3. The compound of  claim 2 , which is 
       
         
           
           
               
               
           
         
       
     
     
       4. The compound of  claim 1 , which is 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable salt thereof. 
     
     
       5. The compound of  claim 4 , which is 
       
         
           
           
               
               
           
         
       
     
     
       6. A pharmaceutical composition comprising a compound of  claim 1  and one or more excipients. 
     
     
       7. A pharmaceutical composition comprising a compound of  claim 2  and one or more excipients. 
     
     
       8. A pharmaceutical composition comprising a compound of  claim 3  and one or more excipients. 
     
     
       9. A pharmaceutical composition comprising a compound of  claim 4  and one or more excipients. 
     
     
       10. A pharmaceutical composition comprising a compound of  claim 5  and one or more excipients.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.