P
USH2043HExpiredUtilityPatentIndex 73

Skin care compositions

Assignee: PROCTER & GAMBLEPriority: May 23, 1997Filed: May 23, 1997Granted: Aug 6, 2002
Est. expiryMay 23, 2017(expired)· nominal 20-yr term from priority
Inventors:DECKNER GEORGE ENDELSANOGUEIRA JR JAMES PEDROSAZUKOWSKI JOSEPH MICHAEL
A61Q 19/00A61K 8/671A61K 2800/52A61Q 19/08
73
PatentIndex Score
6
Cited by
48
References
11
Claims

Abstract

Disclosed are skin care compositions containing retinoids which generally improve the quality of the skin, particularly human facial skin. More particularly, the present invention relates to retinol containing skin care compositions with improved skin compatibility.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
       1. A skin care composition comprising: 
       a.) from about 0.005% to about 2% of a retinoid; and  
       b.) from about 0.001% to about 5% of a preservative component, comprising:  
       i.) a formaldehyde donor; and  
       ii.) a halopropynyl compound selected from the group consisting of iodopropargyl esters, ethers, acetals, carbamates and carbonates and combinations, thereof.  
     
     
       2. A composition according to  claim 1 , wherein the weight ratio of the formaldehyde donor to halopropynyl compound is from about 2000:1 to about 1:1. 
     
     
       3. A composition according to  claim 1 , wherein the halopropynyl compound is 3-iodo-2-propynyl butyl carbamate. 
     
     
       4. A composition according to  claim 1 , which comprises from about 0.05% to about 0.2% of the preservative and wherein the formaldehyde donor is selected from the group consisting of dimethyloldimethyidantoin, N,N″-methylene bis [N′-[hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea]; N-(hydroxymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-N′-(hydroxymethyl) urea; the cis isomer of 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride sodium hydroxymethylglycinate, dimethyl oxazoline 7-ethylbicycloxasolidine, 2-bromo-2-nitropropane-1,3-diol, 5-bromo-5-nitro-1,3-dioxane and mixtures thereof. 
     
     
       5. A composition according to  claim 4 , wherein the formaldehyde donor is dimethyloldimethyldantoin. 
     
     
       6. A composition according to  claim 1 , wherein the retinoid is selected from the group consisting of Vitamin A alcohol, Vitamin A aldehyde, retinyl acetate, retinyl palmitate, and mixtures thereof. 
     
     
       7. A composition according to  claim 1 , wherein said composition further comprises a compound selected from the group consisting of hydroxy acids, desquamatory agents, sunscreens, anti-oxidants, and combinations thereof. 
     
     
       8. A composition according to claim 1 which further comprises from about 1% to about 99.5% of a dermatological carrier. 
     
     
       9. A composition according to  claim 8  in the form of a lotion, a cream, a gel, a stick, a spray, an ointment, a paste, a mousse, or a cosmetic. 
     
     
       10. A method of regulating skin conditioning, comprising applying to the skin of a mammal a safe and effective amount of a composition comprising applying to the skin a safe and effective amount of the composition according to  claim 1 . 
     
     
       11. A method of regulating visible and/or tactile discontinuities in the texture of mammalian skin, comprising applying to the skin of a mammal a safe and effective amount of a composition comprising applying to the skin a safe and effective amount of the composition according to  claim 1 .

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