USH2284HActiveUtilityPatentIndex 40

Vaccines for protecting against influenza

Assignee: STOEHR KLAUSPriority: Apr 27, 2009Filed: Apr 27, 2010Granted: Sep 3, 2013

Est. expiryApr 27, 2029(~2.8 yrs left)· nominal 20-yr term from priority

Inventors:STOEHR KLAUS DORMITZER PHILIP RALPH BROEKER MICHAEL

A61P 37/04A61P 31/16A61K 39/12A61K 2039/70C12N 2760/16234C12N 2760/16134A61K 39/145A61K 2039/55566A61K 39/39

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Claims

Abstract

A live attenuated influenza vaccine contains a H1 subtype influenza A strain. Its hemagglutinin is more closely related to SEQ ID NO: 1 than to SEQ ID NO: 3.

Claims

exact text as granted — not AI-modified

The invention claimed is:  
     
       1. An influenza A virus, wherein (a) the viral hemagglutinin gene encodes a hemagglutinin which is more closely related to SEQ ID NO: 1 than to SEQ ID NO: 3 and (b) at least one other viral gene is from the AA/6/60 influenza A virus strain. 
     
     
       2. An influenza A virus, wherein (a) the viral hemagglutinin gene encodes a hemagglutinin protein which has at least 90% sequence identity to SEQ ID NO: 1, and (b) at least one other viral gene is from the AA/6/60 influenza A virus strain.

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