Hydroquinone derivative

Abstract

Novel hydroquinone derivatives of the formulae (I) and (II), ##STR1## wherein R 1 is an alkyl group having 7 to 11 carbon atoms, ##STR2## wherein each of R 2 to R 5 is independently a hydrogen atom, a lower alkyl group or a lower alkoxy group provided that at least one of R 2 to R 5 is a lower alkyl group or a lower alkoxy group, and R 6 is an alkyl group having a carbon chain of at least 2 carbon atoms. as compounds having antioxidant activity and tumor incidence inhibiting activity, and an antioxidant and a tumor incidence inhibitor containing, as an active ingredient, a hydroquinone derivative of the formula (III), ##STR3## wherein each of R 7 to R 10 is independently a hydrogen atom, a lower alkyl group or a lower alkoxy group, and R 11 is an alkyl group having a carbon chain of at least 2 carton atoms, and/or a salt thereof.

What is claimed is: . .1. A compound of the formula: ##STR20## wherein R 2 , R 3  and R 4  are independently a lower alkyl group or a lower alkoxy group, R 5  is hydrogen and R 6  is a C 4-8   
     
        alkyl group, or a salt thereof..!.2. An antioxidant composition comprising together with a carrier an effective amount of a compound of the formula: ##STR21## wherein R 2 , R 3  and R 4  are independently a lower alkyl group or a lower alkoxy group, R 5  is hydrogen and R 6  is a . .C 4-8  alkyl.!. .Iadd.C 6-8  alkyl .Iaddend.group, or a salt thereof. 
     
     
        .Iadd.    A compound of the formula: ##STR22## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is a C 8  alkyl group, or a salt 
     
     
        thereof. .Iaddend..Iadd.4.  An antioxidant composition comprising together with a carrier an effective amount of a compound of the formula: ##STR23## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is a C 6-8  alkyl group or a 
     
     
        salt thereof. .Iaddend..Iadd.5.  A pharmaceutical composition for the treatment of functional disorders in organs comprising together with a carrier an effective amount of a compound of the formula: ##STR24## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is a C 6-8  alkyl group or a 
     
     
        salt thereof. .Iaddend..Iadd.6.  A pharmaceutical composition for eliminating tissue disorder inducing factors comprising together with a carrier an effective amount of a compound of the formula: ##STR25## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is a C 6-8  alkyl group or a 
     
     
        salt thereof. .Iaddend..Iadd.7.  A pharmaceutical composition for inhibiting tumors comprising together with a carrier an effective amount of a compound of the formula: ##STR26## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is C 6-8  alkyl group or a salt 
     
     
        theref. .Iaddend..Iadd.8.  A composition according to claim 5, 6 or 7 wherein R 2 , R 3  and R 4  are each methyl. .Iaddend..Iadd.9. A compound according to claim 3, wherein R 2 , R 3  and R 4  are 
     
     
        each methyl. .Iaddend..Iadd.10.  A method of treating functional disorders in organs comprising administering to a person in need of same an effective amount of a compound of the formula: ##STR27## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is a C 6-8  alkyl group or a 
     
     
        salt thereof. .Iaddend..Iadd.11.  A method of eliminating tissue disorder inducing factors comprising administering to a person in need of same an effective amount of a compound of the formula: ##STR28## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is a C 6-8  alkyl group or a 
     
     
        salt thereof. .Iaddend..Iadd.12.  A method of inhibiting tumors comprising administering to a person in need of same an effective amount of a compound of the formula: ##STR29## wherein R 2 , R 3  and R 4  are independently a C 1-4  alkyl group, R 5  is hydrogen and R 6  is C 6-8  alkyl group or a salt 
     
     
        thereof. .Iaddend..Iadd.13.  A method according to claim 10, 11 or 12 wherein R 2 , R 3  and R 4  are each methyl. .Iaddend.