Multiple layer softgel

Abstract

A device, and a method for forming a softgel having multiple gelatin layers and softgels having multiple gelatin layers are disclosed. In particular there is provided a device for forming a gelatin sheet having at least two gelatin layers. Each gelatin layer has a thickness. The device comprises a gelatin spreader box which includes at least one opening for extruding a gelatin sheet. The device also includes a first and a second height adjustable gate disposed at least partially across the opening; and a first and a second height adjustment control. Adjustment of the first height adjustment control varies the height of the first gate and adjustment of the second height adjustment control varies the height of the second gate, thereby controlling the thickness of the at least two gelatin layers.

1. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first gelatin layer and a second gelatin layer, each layer having a uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third gelatin layer, the third layer having a uniform thickness wherein the first and second sheets meet at a seam. 
     
     
       2. The softgel capsule of  claim 1  further comprising a fourth gelatin layer that surrounds the third layer. 
     
     
       3. The softgel capsule of  claim 2  wherein the first layer is adjacent the second layer and the third layer is adjacent the fourth layer. 
     
     
       4. The softgel capsule of  claim 2  wherein the first and third layers are a first color and the second and fourth layers are a second color. 
     
     
       5. The softgel capsule of  claim 2  wherein the first and third layers are colored and the second and fourth layers are uncolored. 
     
     
       6. The softgel capsule of  claim 1  wherein the thickness of the first and second gelatin layers are the same. 
     
     
       7. The softgel capsule of  claim 1  wherein the thickness of the first and second gelatin layers are different. 
     
     
       8. The softgel capsule of  claim 1  wherein the first and second layers differ with respect to at least one property selected from the group consisting of degree of permeability, rate of dissolution, mouth feel and taste. 
     
     
       9. The softgel capsule of  claim 1  formed by an apparatus comprising a device for forming the first sheet having at least two gelatin layers. 
     
     
       10. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked gelatin layers of uniform thickness. 
     
     
       11. The softgel of  claim 1  wherein the combined thickness of the first and second layers is approximately equal to the thickness of the third layer. 
     
     
       12. The softgel capsule of  claim 2  wherein the first and third layers are uncolored and the second and fourth layers are colored. 
     
     
       13. The softgel capsule of  claim 2  wherein the first and third layers are a cellulose derivative and gelatin mixture and the second and fourth layers are gelatin. 
     
     
       14. The softgel capsule of  claim 13  wherein the first and third layers are comprised of from about 1% to about 10% cellulose acetate phthalate. 
     
     
       15. The softgel capsule of  claim 2  wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer. 
     
     
       16. The softgel capsule of  claim 15  wherein the second, fourth, fifth, and sixth layers are gelatin and the first and third layers are a cellulose derivative. 
     
     
       17. The softgel of  claim 2  wherein the thickness of the third and fourth layers is the same. 
     
     
       18. The softgel of  claim 2  wherein the thickness of the third and fourth layers is different. 
     
     
       19. The softgel of  claim 1  wherein the first and third layers are colored and the second layer is uncolored. 
     
     
       20. A softgel capsule having opposing ends comprising:
 a first sheet having at least a first gelatin layer that surrounds a second gelatin layer; and  
 a second sheet having at least a third gelatin layer that surrounds a fourth gelatin layer,  
 wherein the first and second sheets cover respective opposing ends of the softgel capsule and fuse together to form a seam.  
 
     
     
       21. The softgel capsule of  claim 20  wherein the combined thickness of the first and second layers is about equal to combined thickness of the third and fourth layers. 
     
     
       22. The softgel capsule of  claim 20  wherein the thickness of each layer is the same. 
     
     
       23. The softgel of  claim 20  wherein the thickness of each layer is different. 
     
     
       24. The softgel of  claim 20  wherein the first, third, and fourth layers are uncolored and the second layer is colored. 
     
     
       25. The softgel of  claim 20  wherein the first and third layers are uncolored and the second and fourth layers are colored. 
     
     
       26. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises cellulose acetate phthalate. 
     
     
       27. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises methyl cellulose. 
     
     
       28. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises ethyl cellulose. 
     
     
       29. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises hydroxypropylmethyl cellulose. 
     
     
       30. The softgel capsule of  claim 26  wherein the first and third layers comprise cellulose acetate phthalate. 
     
     
       31. The softgel capsule of  claim 27  wherein the first and third layers comprise methyl cellulose. 
     
     
       32. The softgel capsule of  claim 28  wherein the first and third layers comprise ethyl cellulose. 
     
     
       33. The softgel capsule of  claim 29  wherein the first and third layers comprise hydroxypropylmethyl cellulose. 
     
     
       34. The softgel capsule of  claim 27  wherein the second and fourth layers comprise methyl cellulose. 
     
     
       35. The softgel capsule of  claim 28  wherein the second and fourth layers comprise ethyl cellulose. 
     
     
       36. The softgel capsule of  claim 29  wherein the second and fourth layers comprise hydroxypropylmethyl cellulose. 
     
     
       37. The softgel capsule of  claim 26  wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises cellulose acetate phthalate. 
     
     
       38. The softgel capsule of  claim 27  wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises methyl cellulose. 
     
     
       39. The softgel capsule of  claim 28  wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises ethyl cellulose. 
     
     
       40. The softgel capsule of  claim 29  wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises hydroxypropylmethyl cellulose. 
     
     
       41. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises cellulose acetate phthalate. 
     
     
       42. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises methyl cellulose. 
     
     
       43. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises ethyl cellulose. 
     
     
       44. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises hydroxypropylmethyl cellulose. 
     
     
       45. The softgel capsule of  claim 26  wherein the second and fourth layers comprise cellulose acetate phthalate.