USRE39355EExpiredUtilityPatentIndex 52
Preparation of human IGF via recombinant DNA technology
Est. expiryJun 6, 2003(expired)· nominal 20-yr term from priority
C07K 2319/00C07K 2319/02C07K 14/65C12N 9/2408C12N 15/81C07K 2319/75A61K 38/00C07K 14/485C07K 2319/036C12N 15/00
52
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Claims
Abstract
Human insulin-like growth factor is synthesized in recombinant cell culture by host cells transformed with expression vectors bearing DNA encoding human insulin-like growth factor.
Claims
exact text as granted — not AI-modified1. A fusion protein comprising the amino acid sequence of mature human IGF-I as shown in FIG. 12 or a natural allelic variant thereof consisting of amino acids residues 20 - 89 of SEQ ID NO: 48 and, at the N-terminus of the mature human IGF-I, a bacterial protein followed by an enzymatic proteolysis site linking the bacterial protein and the mature human IGF-I.
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