P
USRE44698EExpiredUtilityPatentIndex 37

Plants with reduced susceptibility to pathogenic oomycetes

Assignee: DE WIT JACOBUS PETRUS CORNELISPriority: Jun 16, 2004Filed: Jun 10, 2005Granted: Jan 7, 2014
Est. expiryJun 16, 2024(expired)· nominal 20-yr term from priority
Inventors:DE WIT JACOBUS PETRUS CORNELISVAN DUN CORNELIS MARIA PETRUSSCHUT JOANNES WILHELMUSEGELMEERS PETRUS LAMBERTUS JOSEPHUSDIRKS ROBERT HELENE GHISLAIN
A01H 6/14A01H 5/12A01H 5/02
37
PatentIndex Score
0
Cited by
10
References
72
Claims

Abstract

The present invention relates to a for obtaining a plant showing a reduced susceptibility towards infection with a pathogen, in particular an oomycete, comprising treating MO seeds of a plant species to be modified with a mutagenic agent to obtain M1 seeds and growing plants therefrom the thus obtained M1 seeds to obtain M1 plants, inoculation of the thus obtained M1+n plants with the pathogen and selecting plants that show a reduction or absence of sporulation of the pathogen as plants having a reduced susceptibility phenotype. The invention further relates to plants, seeds, pollen, cells and tissues that have the reduced susceptibility towards oomycetes.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A lettuce plant showing a reduced susceptibility towards infection with an oomycete Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility for oomycetes towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41294, 41295, 41296, 41297, 41298, 41299, 41300, 41301, 41302, 41303, 41304, 41305, 41306, 41307, 41308, 41309, 41310, 41311, 41312, 41313, 41314, 41315, 41316, 41317, 41318, 41319, 41320, 41321, 41322 or 41323; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       2. A progeny of a the plant of  claim 1  having all characteristics including reduced susceptibility towards infection with an oomycete, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41294, 41295, 41296, 41297, 41298, 41299, 41300, 41301, 41302, 41303, 41304, 41305, 41306, 41307, 41308, 41309, 41310, 41311, 41312, 41313, 41314, 41315, 41316, 41317, 41318, 41319, 41320, 41321, 41322 or 41323; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       3. A seed of giving rise to a lettuce plant of showing a reduced susceptibility towards infection with an oomycete Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, a representative sample of which seed of which was deposited under NCIMB accession number 41294, 41295, 41296, 41297, 41298, 41299, 41300, 41301, 41302, 41303, 41304, 41305, 41306, 41307, 41308, 41309, 41310, 41311, 41312, 41313, 41314, 41315, 41316, 41317, 41318, 41319, 41320, 41321, 41322 or 41323; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       4. Pollen of the plant of  claim 1 . 
     
     
       5. A cell of the plant of  claim 1 . 
     
     
       6. A tissue of the plant of  claim 1 . 
     
     
       7. A method of producing a lettuce plant, or part thereof, having reduced susceptibility towards infection with an oomycete, Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41298, 41300, 41301, 41304, 41305, 41307, 41310, 41312, 41316, or 41320, and wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated; said method comprising producing progeny from a the plant of claim 1, or part thereof, having reduced susceptibility towards infection with the oomycete, representative seed of which having been deposited under NCIMB accession number 41294, 41295, 41296, 41297, 41298, 41299, 41300, 41301, 41302, 41303, 41304, 41305, 41306, 41307, 41308, 41309, 41310, 41311, 41312, 41313, 41314, 41315, 41316, 41317, 41318, 41319, 41320, 41321, 41322 or 41323. 
     
     
       8. A plant produced from the method of  claim 7 , having all characteristics including reduced susceptibility towards infection with an oomycete as in a lettuce plant showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41294, 41295, 41296, 41297, 41298, 41299, 41300, 41301, 41302, 41303, 41304, 41305, 41306, 41307, 41308, 41309, 41310, 41311, 41312, 41313, 41314, 41315, 41316, 41317, 41318, 41319, 41320, 41321, 41322 or 41323; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       9. A lettuce plant having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41294, 41295, 41296, 41297, 41298, 41299, 41300, 41301, 41302, 41303, 41304, 41305, 41306, 41307, 41308, 41309, 41310, 41311, 41323. 41312, 41313, 41314, 41315, 41316, 41317, 41318, 41319, 41320, 41321, 41322 or 41323. 
     
     
       10. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41298; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       11. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41300; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       12. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41301; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       13. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41304; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       14. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41305; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       15. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41307; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       16. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41310; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       17. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41312; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       18. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41316; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       19. The lettuce plant of claim 1 wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41320; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       20. Pollen of the plant of any one of claims 10-19. 
     
     
       21. A cell of the plant of any one of claims 10-19. 
     
     
       22. A tissue of the plant of any one of claims 10-19. 
     
     
       23. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41298; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       24. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41300; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       25. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41301; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       26. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41304; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       27. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41305; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       28. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41307; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       29. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41310; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       30. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41312; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       31. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41316; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       32. A progeny of the plant of claim 1, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41320; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       33. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41298; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       34. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41300; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       35. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41301; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       36. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41304; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       37. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41305; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       38. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41307; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       39. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41310; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       40. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41312; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       41. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41316; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       42. The seed of claim 3, giving rise to a lettuce plant showing a reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41320; wherein the reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       43. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41298, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       44. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41300, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       45. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41301, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       46. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41304, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       47. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41305, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       48. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41307, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       49. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41310, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       50. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41312, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       51. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41316, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       52. The method of claim 7, comprising producing progeny from a plant, or part thereof, having reduced susceptibility towards Bremia lactucae, wherein the plant has genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant representative seed of which was deposited under NCIMB accession number 41320, and said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       53. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41298; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       54. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41300; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       55. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41301; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       56. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41304; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       57. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41305; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       58. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41307; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       59. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41310; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       60. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41312; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       61. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41316; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       62. The plant of claim 8, showing the reduced susceptibility towards Bremia lactucae and having genetic information in its genome which is responsible for the reduced susceptibility towards Bremia lactucae, wherein the genetic information is as found in a lettuce plant, representative seed of which was deposited under NCIMB accession number 41320; wherein said reduced susceptibility towards Bremia lactucae is not R-gene mediated. 
     
     
       63. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41298. 
     
     
       64. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41300. 
     
     
       65. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41301. 
     
     
       66. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41304. 
     
     
       67. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41305. 
     
     
       68. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41307. 
     
     
       69. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41310. 
     
     
       70. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41312. 
     
     
       71. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41316. 
     
     
       72. The lettuce plant of claim 9, having all characteristics of a lettuce plant grown from seed deposited under NCIMB accession number 41320.

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