P
USRE44718EActiveUtilityPatentIndex 49

Human sebum mimetics derived from botanical sources and methods for making the same

Assignee: INT FLORA TECHNOLOGIES LTDPriority: Oct 26, 2009Filed: Feb 25, 2013Granted: Jan 21, 2014
Est. expiryOct 26, 2029(~3.3 yrs left)· nominal 20-yr term from priority
Inventors:BROWN JAMES SKLEIMAN ROBERTKORITALA SAMBASIVARAOASHLEY DAVID A
A61K 8/922A61Q 19/00A61K 8/31A61K 8/63A61K 8/361A61Q 5/12A61K 8/37
49
PatentIndex Score
0
Cited by
16
References
18
Claims

Abstract

Human sebum mimetics and methods for producing human sebum mimetics are provided. In one exemplary embodiment, a human sebum mimetic comprises a wax ester derived from interesterification refined botanical oil comprising palmitoleic acid and refined jojoba oil, a phytosterol, and phytosqualene. A method for producing a human sebum mimetic comprises mixing refined macadamia oil and refined jojoba oil, interesterifying the refined macadamia oil and the refined jojoba oil, adding a phytosterol after the interesterifying, and adding phytosqualene after the interesterifying.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A method for producing a human sebum mimetic comprising the steps of:
 mixing a refined macadamia oil and a refined jojoba oil; 
 interesterifying the refined macadamia oil and the refined jojoba oil to produce a wax ester; 
 adding a phytosterol; 
 adding phytosqualene after the step of interesterifying; and 
 producing the human sebum mimetic. 
 
     
     
       2. The method of  claim 1 , wherein the step of mixing comprises mixing an amount of refined macadamia oil of about 45 to about 65 wt. %. of the human sebum mimetic with the refined jojoba oil. 
     
     
       3. The method of  claim 2 , wherein the step of mixing comprises mixing the amount of refined macadamia oil of about 51 to about 55 wt. % of the human sebum mimetic with the refined jojoba oil. 
     
     
       4. The method of  claim 1 , wherein the step of mixing comprises mixing an amount of refined jojoba oil of about 20 to about 35 wt. % of the human sebum mimetic with the refined macadamia oil. 
     
     
       5. The method of  claim 4 , wherein the step of mixing comprises mixing the amount of refined jojoba oil of about 20 to about 33 wt. % of the human sebum mimetic with the refined macadamia oil. 
     
     
       6. The method of  claim 1 , wherein the step of adding the phytosterol comprises adding an amount of the phytosterol of about 0.5 to about 10 wt. % of the human sebum mimetic. 
     
     
       7. The method or  claim 6 , wherein the step of adding the phytosterol comprises adding the amount of the phytosterol of about 1 to about 5 wt. % of the human sebum mimetic. 
     
     
       8. The method of  claim 1 , wherein the step of adding the phytosqualene comprises adding an amount of the phytosqualene of about 5 to about 20 wt. % of the human sebum mimetic. 
     
     
       9. The method of  claim 8 , wherein the step of adding the phytosqualene comprises adding the amount of the phytosqualene of about 11 to about 15 wt. % of the human sebum mimetic. 
     
     
       10. The method of  claim 1 , further comprising adding a tocopherol after the step of interesterifying. 
     
     
       11. The method of  claim 1 , further comprising adding a functional additive after the step of interesterifying. 
     
     
       12. The method of  claim 1 , further comprising bleaching the human sebum mimetic after the steps of adding the phytosqualene and adding the phytosterol. 
     
     
       13. The method of  claim 1 , further comprising the step of deodorizing the human sebum mimetic after the step of adding the phytosqualene and adding the phytosterol. 
     
     
       14. The method of  claim 1 , wherein the adding the phytosterol is after the step of interesterifying the refined macadamia oil and the refined jojoba oil. 
     
     
       15. The method of  claim 1 , wherein the adding the phytosterol is before the step of interesterifying the refined macadamia oil and the refined jojoba oil. 
     
     
       16. The method of  claim 11 , wherein the functional additive is at least one of a tocopherol, a fragrance, a dye, a pigment, a preservative, an antioxidant, a moisturizer, an emollient, and a thickener. 
     
     
       17. The method of  claim 1 , wherein the human sebum mimetic is added to a personal care product. 
     
     
       18. The method of  claim 17 , wherein the personal care product is a hair conditioning lotion.

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