USRE47221EActiveUtility

Tricyclic compounds

97
Assignee: ABBVIE INCPriority: Dec 1, 2009Filed: Mar 1, 2017Granted: Feb 5, 2019
Est. expiryDec 1, 2029(~3.4 yrs left)· nominal 20-yr term from priority
Inventors:Neil WishartKristine E. FrankMichael FriedmanDawn M. GeorgeKent D. StewartGrier A. Wallace
A61P 9/00A61P 39/04A61P 7/06A61P 35/04A61P 5/14A61P 9/04A61P 5/02A61P 37/02A61P 9/08A61P 39/00A61P 5/38A61P 7/10A61P 7/02A61P 9/12A61P 37/08A61P 43/00A61P 3/10A61P 5/06A61P 7/00A61P 7/04A61P 37/06A61P 37/00A61P 7/08A61P 9/10A61P 5/10A61P 31/18A61P 25/14A61P 33/14A61P 33/02A61P 31/20A61P 25/00A61P 31/12A61P 25/16A61P 31/04A61P 27/06A61P 31/10A61P 35/00A61P 31/14A61P 25/22A61P 35/02A61P 27/02A61P 31/16A61P 25/28A61P 29/00A61P 21/04A61P 15/08A61P 17/02A61P 1/16A61P 11/06A61P 13/02A61P 13/12A61P 1/04A61P 17/06A61P 11/16A61P 11/00A61P 19/00A61P 19/02A61P 17/00A61P 17/14C07D 498/14C07D 513/14C07D 471/14C07D 487/14A61K 31/4985A61K 31/437A61K 2300/00C07D 401/12A61K 45/06
97
PatentIndex Score
42
Cited by
161
References
14
Claims

Abstract

The invention provides compounds of Formula (I) and Formula (II) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Claims

exact text as granted — not AI-modified
What is claimed: 
     
       1. A compound selected from 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       2. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       3. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       4. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       5. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       6. A compound selected from 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       7. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       8. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       9. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       10. A compound selected from 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       11. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       12. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
         or pharmaceutically acceptable salts, stereoisomers and isomers thereof. 
       
     
     
       13. A compound represented by the following structure: 
       
         
           
           
               
               
           
         
       
       or a pharmaceutically acceptable salt thereof. 
     
     
       14. The compound according to claim 13 represented by the following structure:

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