P
USRE49708EExpiredUtilityPatentIndex 59

Nucleic acid molecules encoding indoleamine 2,3-dioxygenase-2

Assignee: LANKENAU INST MEDICAL RESPriority: May 18, 2006Filed: Jan 8, 2021Granted: Oct 24, 2023
Est. expiryMay 18, 2026(expired)· nominal 20-yr term from priority
Inventors:PRENDERGAST GEORGE CMETZ RICHARD
C12N 9/0069A01K 67/0276C12Q 1/26C07K 2319/21C07K 2319/40C12N 2830/006
59
PatentIndex Score
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Cited by
12
References
8
Claims

Abstract

The nucleotide and amino acid sequences of indoleamine 2,3-dioxygenase-2 (IDO2) and methods of use thereof are provided.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. An isolated cDNA nucleic acid molecule encoding an indoleamine 2,3-dioxygenase-2 (IDO2) protein comprising an amino acid sequence having at least 90% identity with SEQ ID NO: 1. 
     
     
       2. The nucleic acid molecule of  claim 1 , wherein said amino acid sequence has at least 95% identity with SEQ ID NO: 1. 
     
     
       3. The nucleic acid molecule of  claim 1 , wherein said amino acid sequence has at least 97% identity with SEQ ID NO: 1. 
     
     
       4. The nucleic acid molecule of  claim 1 , wherein said amino acid sequence has at least 99% identity with SEQ ID NO: 1. 
     
     
       5. The nucleic acid molecule of  claim 1 , wherein said amino acid sequence is SEQ ID NO: 1. 
     
     
       6. An isolated nucleic acid molecule encoding an indoleamine 2,3-dioxygenase-2 (IDO2) protein comprising an amino acid sequence having at least 90% identity with SEQ ID NO: 1, wherein said nucleic acid molecule is present in a vector.  
     
     
       7. The isolated nucleic acid molecule of claim 6, wherein said vector is a virus vector or a plasmid.  
     
     
       8. The isolated nucleic acid molecule of claim 6, wherein the encoding sequence is cDNA.

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