Assignee
JOLLA PHARMA
US32 patents
Top patents by PatentIndex Score
US5552391ASep 3, 1996
Chemically-defined non-polymeric valency platform molecules and conjugates thereof
JOLLA PHARMA160 citations98
US5817752AOct 6, 1998
Cyclic polypeptides comprising a thioether linkage and methods for their preparation
JOLLA PHARMA65 citations96
US5276013AJan 4, 1994
Conjugates of biologically stable polyfunctional molecules and polynucleotides for treating systemic lupus erythematosus
JOLLA PHARMA59 citations96
US6207160B1Mar 27, 2001
aPL immunoreactive peptides, conjugates thereof and methods of treatment for aPL antibody-mediated pathologies
JOLLA PHARMA70 citations95
US5726329AMar 10, 1998
Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides
JOLLA PHARMA53 citations95
US5606047AFeb 25, 1997
Chemically-defined non-polymeric valency platform molecules and conjugates thereof
JOLLA PHARMA65 citations95
US6060056AMay 9, 2000
Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule
JOLLA PHARMA58 citations94
US6031073AFeb 29, 2000
Cyclic polypeptides comprising a thioether linkage and methods for their preparation
JOLLA PHARMA33 citations93
US5268454ADec 7, 1993
Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier
JOLLA PHARMA42 citations93
US7351855B2Apr 1, 2008
Chemically defined non-polymeric valency platform molecules and conjugates thereof
JOLLA PHARMA24 citations92
US6951939B2Oct 4, 2005
Multivalent platform molecules comprising high molecular weight polyethylene oxide
JOLLA PHARMA18 citations92
US5874552AFeb 23, 1999
Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides
JOLLA PHARMA29 citations92
US5633395AMay 27, 1997
Chemically-defined non-polymeric valency platform molecules and conjugates thereof
JOLLA PHARMA33 citations92
US5162515ANov 10, 1992
Conjugates of biologically stable polymers and polynucleotides for treating systemic lupus erythematosus
JOLLA PHARMA40 citations92
US6410775B1Jun 25, 2002
APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
JOLLA PHARMA18 citations91
US6399578B1Jun 4, 2002
Conjugates comprising galactose α1,3 galactosyl epitopes and methods of using same
JOLLA PHARMA21 citations91
US5874409AFeb 23, 1999
APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
JOLLA PHARMA42 citations90
US6858210B1Feb 22, 2005
Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same
JOLLA PHARMA33 citations88
US6458953B1Oct 1, 2002
Valency platform molecules comprising carbamate linkages
JOLLA PHARMA16 citations84
US6166198ADec 26, 2000
Methods for oligonucleotide synthesis
JOLLA PHARMA12 citations73
US5017648AMay 21, 1991
D-GL conjugate therapy
JOLLA PHARMA7 citations73
US4950469AAug 21, 1990
D-GL conjugate therapy
JOLLA PHARMA12 citations73
US4950713AAug 21, 1990
Conjugates of D-glutamic acid: D-lysine copolymer and certain biochemicals
JOLLA PHARMA9 citations73
US7163683B2Jan 16, 2007
Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule
JOLLA PHARMA9 citations71
US7138244B2Nov 21, 2006
Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule
JOLLA PHARMA7 citations70
US7081242B1Jul 25, 2006
Methods of treating lupus based on antibody affinity and screening methods and compositions for use thereof
JOLLA PHARMA9 citations63
US8877263B2Nov 4, 2014
Modified pectins, compositions and methods related thereto
JOLLA PHARMA2 citations61
US8722111B2May 13, 2014
Modified pectins, compositions and methods related thereto
JOLLA PHARMA2 citations61
US8658224B2Feb 25, 2014
Modified pectins, compositions and methods related thereto
JOLLA PHARMA1 citations61
US7208156B2Apr 24, 2007
Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule
JOLLA PHARMA2 citations60
US7115581B2Oct 3, 2006
Chemically-defined non-polymeric valency platform molecules and conjugates thereof
JOLLA PHARMA1 citations52
US9181354B2Nov 10, 2015
Modified pectins, compositions and methods related thereto
JOLLA PHARMA0 citations51