Inventor

HIRAI YOSHIKATSU

JP17 patents

Patents

17 patents

US5348858ASep 20, 1994

Monoclonal antibody specific for human interleukin-1β and method for detection of biologically active human interleukin-1β

OTSUKA PHARMA CO LTD41 citations90

US5837230ANov 17, 1998

Methods of treating allergies with M-CSF

OTSUKA PHARMA CO LTD15 citations82

US5342615AAug 30, 1994

Method for treating arthritis or inflammation with Il-1α or derivatives thereof

OTSUKA PHARMA CO LTD10 citations82

US4898818AFeb 6, 1990

Antitumor active substance, process for preparing the same, drug containing the substance, gene coding for the substance, vector containing the gene and recombinant microorganism

OTSUKA PHARMA CO LTD22 citations81

US5849282ADec 15, 1998

Method of treating colon, renal, and lung carcinomas with γ-interferon and Ser71 !-interleukin-1β

OTSUKA PHARMA CO LTD17 citations80

US4675291AJun 23, 1987

Human cultured cell line

OTSUKA PHARMA CO LTD12 citations74

US5342614AAug 30, 1994

Method of treating arthritus or inflammation with IL-1β or derivatives thereof

OTSUKA PHARMA CO LTD5 citations73

US5702698ADec 30, 1997

Methods of use of IL-1α

OTSUKA PHARMA CO LTD8 citations72

US5543140AAug 6, 1996

Method and use of IL-1α

OTSUKA PHARMA CO LTD7 citations72

US5120534AJun 9, 1992

IL-1α derivatives and medicament for treating thrombocytopenia

OTSUKA PHARMA CO LTD6 citations72

US5008374AApr 16, 1991

IL-1α derivatives and drugs

OTSUKA PHARMA CO LTD8 citations72

US5650297AJul 22, 1997

DNA encoding human colony-stimulating factors

OTSUKA PHARMA CO LTD11 citations69

US5217714AJun 8, 1993

Method for stimulating the secretion of acth by administration of il-1b analogues

OTSUKA PHARMA CO LTD10 citations67

US6107465AAug 22, 2000

IL-1β and derivatives thereof and drugs

OTSUKA PHARMA CO LTD3 citations61

US5847098ADec 8, 1998

DNA encoding interleukin IL-1β mutant

OTSUKA PHARMA CO LTD3 citations61

US5371204ADec 6, 1994

Gene that encodes for polypeptides of IL-1α

OTSUKA PHARMA CO LTD2 citations61

US5756675AMay 26, 1998

IL-1α derivatives

OTSUKA PHARMA CO LTD0 citations51