Inventor
SILVERMAN RICHARD B
US106 patents
⚠️ This page may combine multiple inventors who share the name “SILVERMAN RICHARD B”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
UNIV NORTHWESTERN
43 patentsUS6028214AFeb 22, 2000
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN114 citations99
US6117906ASep 12, 2000
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN98 citations98
US5563175AOct 8, 1996
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN215 citations98
US6197819B1Mar 6, 2001
Gamma amino butyric acid analogs and optical isomers
UNIV NORTHWESTERN80 citations97
US6794413B1Sep 21, 2004
Compounds and related methods for inhibition of γ-aminobutyric acid aminotransferase
UNIV NORTHWESTERN45 citations96
US5608090AMar 4, 1997
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN21 citations96
US5599973AFeb 4, 1997
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN90 citations96
US6359169B1Mar 19, 2002
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN33 citations95
US5847151ADec 8, 1998
Gaba and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN19 citations95
US5710304AJan 20, 1998
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN26 citations95
US5684189ANov 4, 1997
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN21 citations95
US7381748B1Jun 3, 2008
Compounds and related methods for inhibition of gamma-aminobutyric acid aminotransferase
UNIV NORTHWESTERN15 citations93
US9878996B2Jan 30, 2018
2-imidazolyl-pyrimidine scaffolds as potent and selective inhibitors of neuronal nitric oxide synthase
UNIV NORTHWESTERN40 citations92
US9670141B2Jun 6, 2017
(S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and hepatocellular carcinoma
UNIV NORTHWESTERN26 citations92
US7470790B2Dec 30, 2008
Heteroaromatic selective inhibitors of neuronal nitric oxide synthase
UNIV NORTHWESTERN33 citations92
US9758507B2Sep 12, 2017
Chiral synthesis of pyrrolidine core compounds en route to neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN4 citations84
US9682950B2Jun 20, 2017
Thiophene-2-carboximidamide based selective neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN4 citations84
US9242957B2Jan 26, 2016
Thiophene-2-carboximidamide based selective neuronal nitric oxide inhibitors
UNIV NORTHWESTERN8 citations84
US8932842B2Jan 13, 2015
Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition
UNIV NORTHWESTERN8 citations84
US8735606B2May 27, 2014
Thiophene-2-carboximidamide based selective neuronal nitric oxide inhibitors
UNIV NORTHWESTERN7 citations84
US10442812B2Oct 15, 2019
Substituted 4-methyl-pyrrolo[1,2-a]pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
UNIV NORTHWESTERN7 citations83
US10227352B2Mar 12, 2019
Substituted 4-methyl-pyrrolo[1,2-A]pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
UNIV NORTHWESTERN6 citations83
US10167260B2Jan 1, 2019
2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN4 citations83
US10040799B2Aug 7, 2018
Substituted 4-methyl-pyrrolo[1,2-A]pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
UNIV NORTHWESTERN8 citations83
US9802942B2Oct 31, 2017
Substituted 4-methyl-pyrrolo[1,2-A]pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
UNIV NORTHWESTERN11 citations83
US9732037B2Aug 15, 2017
2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN4 citations83
US9416106B2Aug 16, 2016
2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN6 citations83
US9120750B2Sep 1, 2015
2-Aminopyridine-based selective neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN8 citations83
US9993449B2Jun 12, 2018
(S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and hepatocellular carcinoma
UNIV NORTHWESTERN13 citations82
US9856231B2Jan 2, 2018
Tetrahydrothiophene-based GABA aminotransferase inactivators
UNIV NORTHWESTERN5 citations82
US6342529B1Jan 29, 2002
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN7 citations82
US6291526B1Sep 18, 2001
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN7 citations82
US6140366AOct 31, 2000
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN7 citations82
US9212144B2Dec 15, 2015
2-aminoquinoline-based compounds for potent and selective neuronal nitric oxide synthase inhibition
UNIV NORTHWESTERN8 citations81
US6255345B1Jul 3, 2001
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN8 citations81
US7994326B2Aug 9, 2011
Potent and highly selective heteroaromatic inhibitors of neuronal nitric oxide synthase
UNIV NORTHWESTERN14 citations79
US6525096B1Feb 25, 2003
GABA and L-glutamic acid analogs for antiseizure treatment
UNIV NORTHWESTERN2 citations74
US6416861B1Jul 9, 2002
Organosilicon compounds and uses thereof
UNIV NORTHWESTERN11 citations74
US9765055B2Sep 19, 2017
Intramolecular hydrogen-bonded nitric oxide synthase inhibitors
UNIV NORTHWESTERN4 citations73
US9603820B2Mar 28, 2017
Ornithine aminotransferase inhibition with GABA analogues for treatment of hepatocellular carcinoma
UNIV NORTHWESTERN4 citations73
US9212161B2Dec 15, 2015
Chiral synthesis of pyrrolidine core compounds en route to neuronal nitric oxide synthase inhibitors
UNIV NORTHWESTERN4 citations73
US8829187B1Sep 9, 2014
Chiral pyrrolidine core compounds en route to inhibitors of nitric oxide synthase
UNIV NORTHWESTERN4 citations73
US6274557B1Aug 14, 2001
Inhibition of nitric oxide synthase by amino acids and dipeptides
UNIV NORTHWESTERN8 citations73
SILVERMAN RICHARD B
5 patentsUS8969413B2Mar 3, 2015
Methods of using (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid
SILVERMAN RICHARD B17 citations84
US8557552B2Oct 15, 2013
Selective neuronal nitric oxide synthase inhibitors
SILVERMAN RICHARD B10 citations84
US8697879B2Apr 15, 2014
Chiral synthesis of pyrrolidine core compounds en route to neuronal nitric oxide synthase inhibitors
SILVERMAN RICHARD B4 citations83
US8299100B2Oct 30, 2012
Potent and selective neuronal nitric oxide synthase inhibitors with improved membrane permeability
SILVERMAN RICHARD B10 citations83
US8278084B2Oct 2, 2012
Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition
SILVERMAN RICHARD B10 citations83
LYSOSOMAL THERAPEUTICS INC
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