Inventor · disambiguated record
Brian Froehler
Also filed as: FROEHLER BRIAN · FROEHLER BRIAN C · FROEHLER BRIAN CARL
26 granted patents·10,864 citations·filing 1986–2003
98Inventor score
Files withGILEAD SCIENCES INC10ISIS PHARMACEUTICALS INC9GENENTECH INC3FROEHLER BRIAN C2GILEAD SCIENCES2
Top patents by PatentIndex Score
26 records- 0199US5594121AEnhanced triple-helix and double-helix formation with oligomers containing modified purinesGILEAD SCIENCES INC·Filed 1995·Granted Jan 14, 1997·1.4k cites·58 claims
- 0299US5484908AOligonucleotides containing 5-propynyl pyrimidinesGILEAD SCIENCES INC·Filed 1991·Granted Jan 16, 1996·1.7k cites·18 claims
- 0398US5830653AMethods of using oligomers containing modified pyrimidinesGILEAD SCIENCES INC·Filed 1995·Granted Nov 3, 1998·1k cites·15 claims
- 0498US5721218AOligonucleotides with inverted polarityGILEAD SCIENCES INC·Filed 1996·Granted Feb 24, 1998·457 cites·2 claims
- 0598US5399676AOligonucleotides with inverted polarityGILEAD SCIENCES·Filed 1990·Granted Mar 21, 1995·1.4k cites·32 claims
- 0697US5565555ANucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analoguesGILEAD SCIENCES INC·Filed 1995·Granted Oct 15, 1996·383 cites·10 claims
- 0797US5527899AOligonucleotides with inverted polarityGILEAD SCIENCES INC·Filed 1993·Granted Jun 18, 1996·480 cites·25 claims
- 0897US5194599AHydrogen phosphonodithioate compositionsGILEAD SCIENCES INC·Filed 1988·Granted Mar 16, 1993·463 cites·10 claims
- 0997US4959463AIntermediatesGENENTECH INC·Filed 1986·Granted Sep 25, 1990·164 cites·25 claims
- 1096US6875593B2Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidinesISIS PHARMACEUTICALS INC·Filed 2002·Granted Apr 5, 2005·102 cites·7 claims
- 1196US5256775AExonuclease-resistant oligonucleotidesGILEAD SCIENCES INC·Filed 1990·Granted Oct 26, 1993·928 cites·20 claims
- 1295US6380368B1Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidinesISIS PHARMACEUTICALS INC·Filed 1996·Granted Apr 30, 2002·282 cites·27 claims
- 1395US6235887B1Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidinesISIS PHARMACEUTICALS INC·Filed 1994·Granted May 22, 2001·264 cites·7 claims
- 1495US5672697ANucleoside 5'-methylene phosphonatesGILEAD SCIENCES INC·Filed 1991·Granted Sep 30, 1997·527 cites·8 claims
- 1595US5645985AEnhanced triple-helix and double-helix formation with oligomers containing modified pyrimidinesGILEAD SCIENCES INC·Filed 1992·Granted Jul 8, 1997·968 cites·18 claims
- 1693US5264566AMethod for in vitro oligonucleotide synthesis using H-phosphonatesGENENTECH INC·Filed 1990·Granted Nov 23, 1993·174 cites·11 claims
- 1785US6495672B1Oligonucleotides including 2-aminopyridine and 2-pyridone C-nucleoside unitsISIS PHARMACEUTICALS INC·Filed 2000·Granted Dec 17, 2002·11 cites·2 claims
- 1876US7057027B2Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidinesISIS PHARMACEUTICALS INC·Filed 2003·Granted Jun 6, 2006·4 cites·20 claims
- 1975US6962783B2Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidinesISIS PHARMACEUTICALS INC·Filed 2001·Granted Nov 8, 2005·4 cites·6 claims
- 2073US6447998B12-Aminopyridine and 2-pyridone C-nucleosides, oligonucleotides comprising, and tests using the same oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1997·Granted Sep 10, 2002·12 cites·13 claims
- 2172US5548076AMethod of making oligonucleotides, oligonucleoside thiophosphates and oligonucleoside phosphotriesters using H-phosphonate intermediatesGENENTECH INC·Filed 1993·Granted Aug 20, 1996·20 cites·22 claims
- 2270US5204455AMonomethoxytrityl protected oligonucleotides bound to a solid supportFROEHLER BRIAN C·Filed 1992·Granted Apr 20, 1993·30 cites·10 claims
- 2364US5164491ALarge scale synthesis of oligonucleotides and their associated analogsGILEAD SCIENCES·Filed 1989·Granted Nov 17, 1992·18 cites·14 claims
- 2462US6300486B1Large scale synthesis of oligonucleotides and their associated analogsISIS PHARMACEUTICALS INC·Filed 1998·Granted Oct 9, 2001·17 cites·3 claims
- 2560US8653248B22-aminopyridine and 2-pyridone C-nucleosidesFROEHLER BRIAN C·Filed 2002·Granted Feb 18, 2014·0 cites·4 claims
- 2642US6756496B1Nucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analoguesISIS PHARMACEUTICALS INC·Filed 1997·Granted Jun 29, 2004·3 cites·13 claims
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →