Inventor · disambiguated record
Brian Zambrowicz
Also filed as: ZAMBROWICZ BRIAN
69 granted patents·120 pending applications·668 citations·filing 1996–2025
99Inventor score
Files withLEXICON GENETICS INC53REGENERON PHARMA34ABUIN ALEJANDRO8LEXICON PHARMACEUTICALS INC6LANTHORN THOMAS HERBERT4
Top patents by PatentIndex Score
189 records- 0196US11781131B2CRISPR/Cas dropout screening platform to reveal genetic vulnerabilities associated with tau aggregationREGENERON PHARMA·Filed 2020·Granted Oct 10, 2023·5 cites·36 claims
- 0295US11845931B2CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregationREGENERON PHARMA·Filed 2020·Granted Dec 19, 2023·4 cites·37 claims
- 0394US6582957B1Lipoxygenase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Jun 24, 2003·32 cites·3 claims
- 0493US12209238B2CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregationREGENERON PHARMA·Filed 2023·Granted Jan 28, 2025·1 cites·42 claims
- 0593US6080576AVectors for gene trapping and gene activationLEXICON GENETICS INC·Filed 1998·Granted Jun 27, 2000·156 cites·21 claims
- 0691US6136566AIndexed library of cells containing genomic modifications and methods of making and utilizing the sameLEXICON GENETICS INC·Filed 1996·Granted Oct 24, 2000·118 cites·23 claims
- 0789US12110502B2Models of tauopathyREGENERON PHARMA·Filed 2023·Granted Oct 8, 2024·1 cites·42 claims
- 0889US11845957B2Models of tauopathyREGENERON PHARMA·Filed 2020·Granted Dec 19, 2023·2 cites·51 claims
- 0989US6531309B1Human transporter proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2001·Granted Mar 11, 2003·30 cites·4 claims
- 1089US6436707B1Vectors for gene mutagenesis and gene discoveryLEXICON GENETICS INC·Filed 1999·Granted Aug 20, 2002·79 cites·15 claims
- 1188US12421512B2CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregationREGENERON PHARMA·Filed 2024·Granted Sep 23, 2025·0 cites·32 claims
- 1287US11519004B2Transcription modulation in animals using CRISPR/Cas systemsREGENERON PHARMA·Filed 2019·Granted Dec 6, 2022·4 cites·35 claims
- 1387US10106569B2Inhibitors of sodium glucose transporter 1 for constipationLEXICON PHARMACEUTICALS INC·Filed 2017·Granted Oct 23, 2018·5 cites·1 claims
- 1487US9688710B2Inhibitors of sodium glucose cotransporter 1LEXICON PHARMACEUTICALS INC·Filed 2015·Granted Jun 27, 2017·5 cites·8 claims
- 1587US6716614B1Human calcium dependent proteases, polynucleotides encoding the same, and uses thereofLEXICON GENETICS INC·Filed 2002·Granted Apr 6, 2004·12 cites·3 claims
- 1685US9200025B2Inhibitors of sodium glucose cotransporter 1LEXICON PHARMACEUTICALS INC·Filed 2013·Granted Dec 1, 2015·7 cites·15 claims
- 1784US6207371B1Indexed library of cells containing genomic modifications and methods of making and utilizing the sameLEXICON GENETICS INC·Filed 1997·Granted Mar 27, 2001·57 cites·38 claims
- 1883US6139833ATargeted gene discoveryLEXICON GENETICS INC·Filed 1997·Granted Oct 31, 2000·68 cites·6 claims
- 1982US12391920B2Models of tauopathyREGENERON PHARMA·Filed 2024·Granted Aug 19, 2025·0 cites·27 claims
- 2080US11622547B2Genetically modified mouse that expresses human albuminREGENERON PHARMA·Filed 2020·Granted Apr 11, 2023·1 cites·12 claims
- 2180US11470828B2Rodent model of mood disordersREGENERON PHARMA·Filed 2020·Granted Oct 18, 2022·1 cites·24 claims
- 2280US11130999B2Cas-ready mouse embryonic stem cells and mice and uses thereofREGENERON PHARMA·Filed 2018·Granted Sep 28, 2021·1 cites·36 claims
- 2380US6776988B2Vectors for gene mutagenesis and gene discoveryLEXICON GENETICS INC·Filed 2002·Granted Aug 17, 2004·6 cites·9 claims
- 2479US11021719B2Methods and compositions for assessing CRISPER/Cas-mediated disruption or excision and CRISPR/Cas-induced recombination with an exogenous donor nucleic acid in vivoREGENERON PHARMA·Filed 2018·Granted Jun 1, 2021·1 cites·30 claims
- 2578US6403784B1Human uncoupling proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Jun 11, 2002·5 cites·5 claims
- 2678US2024093316A1Cas-ready mouse embryonic stem cells and mice and uses thereofREGENERON PHARMA·Filed 2023·Application pending·0 cites
- 2777US7268222B1Polynucleotides encoding human transporter proteinsLEXICON PHARMACEUTICALS INC·Filed 2000·Granted Sep 11, 2007·11 cites·4 claims
- 2877US2025280805A1Methods for producing antigen-binding proteins against foreign antigensREGENERON PHARMA·Filed 2025·Application pending·0 cites
- 2976US6767736B2Human ion channel protein and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2001·Granted Jul 27, 2004·7 cites·6 claims
- 3076US2023416728A1Crispr/cas dropout screening platform to reveal genetic vulnerabilities associated with tau aggregationREGENERON PHARMA·Filed 2023·Application pending·0 cites
- 3175US11326184B2Methods and compositions for targeted genetic modification through single-step multiple targetingREGENERON PHARMA·Filed 2015·Granted May 10, 2022·1 cites·32 claims
- 3275US6852521B2Human proteases and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2003·Granted Feb 8, 2005·2 cites·1 claims
- 3375US6649399B2Human proteases and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Nov 18, 2003·2 cites·5 claims
- 3475US2024301442A1Methods and compositions for insertion of antibody coding sequences into a safe harbor locusREGENERON PHARMA·Filed 2024·Application pending·0 cites
- 3574US12342801B2Methods for producing antigen-binding proteins against foreign antigensREGENERON PHARMA·Filed 2021·Granted Jul 1, 2025·0 cites·20 claims
- 3674US12317874B2Method of using a genetically modified mouse that expresses human albuminREGENERON PHARMA·Filed 2023·Granted Jun 3, 2025·0 cites·30 claims
- 3773US11866794B2Cas-ready mouse embryonic stem cells and mice and uses thereofREGENERON PHARMA·Filed 2021·Granted Jan 9, 2024·0 cites·18 claims
- 3873US6716616B1Human kinase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Apr 6, 2004·2 cites·10 claims
- 3973US6692947B2Human transferase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Feb 17, 2004·2 cites·5 claims
- 4073US6555669B2Human transferase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2001·Granted Apr 29, 2003·2 cites·6 claims
- 4172US6743621B2Human proteases and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2002·Granted Jun 1, 2004·1 cites·3 claims
- 4272US6743907B1Human proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Jun 1, 2004·1 cites·5 claims
- 4372US6720412B2Human thrombospondin repeat proteins and polynucleotides encoding the sameLEXICON GENETICS CORP·Filed 2001·Granted Apr 13, 2004·3 cites·5 claims
- 4471US6806073B2Human kinase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2003·Granted Oct 19, 2004·1 cites·1 claims
- 4571US6777221B2Human proteases and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2002·Granted Aug 17, 2004·1 cites·3 claims
- 4671US6602698B2Human kinase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Aug 5, 2003·1 cites·8 claims
- 4771US6509456B2Human proteases and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2001·Granted Jan 21, 2003·1 cites·2 claims
- 4871US6462186B1Human ATPase proteins and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Oct 8, 2002·1 cites·3 claims
- 4971US6441154B1Human proteases and polynucleotides encoding the sameLEXICON GENETICS INC·Filed 2000·Granted Aug 27, 2002·1 cites·2 claims
- 5071US2023337645A1Nuclease-mediated repeat expansionREGENERON PHARMA·Filed 2023·Application pending·0 cites
Showing the top 50 of 189 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →