Inventor · disambiguated record
J. Keith Joung
Also filed as: JOUNG J K · JOUNG J KEITH
75 granted patents·34 pending applications·1,792 citations·filing 1997–2024
99Inventor score
Files withMASSACHUSETTS GEN HOSPITAL94MASSACHUSETTS INST TECHNOLOGY3BEAM THERAPEUTICS INC2JOUNG J K2JOUNG J KEITH2
Top patents by PatentIndex Score
109 records- 0198US11168338B2RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic lociMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted Nov 9, 2021·17 cites·10 claims
- 0298US11098326B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted Aug 24, 2021·16 cites·14 claims
- 0398US10844403B2Increasing specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Nov 24, 2020·31 cites·30 claims
- 0498US10544433B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jan 28, 2020·34 cites·10 claims
- 0598US10526591B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jan 7, 2020·19 cites·32 claims
- 0698US10138476B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Nov 27, 2018·35 cites·28 claims
- 0798US10093910B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Oct 9, 2018·26 cites·30 claims
- 0898US9944912B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Apr 17, 2018·25 cites·33 claims
- 0998US9926546B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Mar 27, 2018·52 cites·32 claims
- 1098US9885033B2Increasing specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Feb 6, 2018·95 cites·3 claims
- 1198US9752132B2Engineered CRISPR-CAS9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Sep 5, 2017·48 cites·24 claims
- 1298US9567603B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Feb 14, 2017·86 cites·10 claims
- 1398US9512446B1Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Dec 6, 2016·164 cites·27 claims
- 1497US12241096B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2023·Granted Mar 4, 2025·4 cites·25 claims
- 1597US11920152B2Increasing specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted Mar 5, 2024·4 cites·9 claims
- 1697US10760064B2RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic lociMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Sep 1, 2020·38 cites·20 claims
- 1797US10633642B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Apr 28, 2020·12 cites·27 claims
- 1897US10415059B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Sep 17, 2019·43 cites·31 claims
- 1997US10378027B2RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic lociMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Aug 13, 2019·18 cites·11 claims
- 2097US10119133B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Nov 6, 2018·39 cites·11 claims
- 2197US9926545B2Engineered CRISPR-CAS9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Mar 27, 2018·18 cites·33 claims
- 2297US9850484B2Comprehensive in vitro reporting of cleavage events by sequencing (Circle-seq)MASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Dec 26, 2017·19 cites·19 claims
- 2397US9567604B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Feb 14, 2017·87 cites·17 claims
- 2496US10202589B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Feb 12, 2019·10 cites·43 claims
- 2596US9988674B2Full interrogation of nuclease DSBs and sequencing (find-seq)MASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Jun 5, 2018·12 cites·18 claims
- 2696US9822407B2Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)MASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Nov 21, 2017·23 cites·12 claims
- 2795US11634731B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted Apr 25, 2023·6 cites·19 claims
- 2895US10767168B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Sep 8, 2020·7 cites·19 claims
- 2995US10501794B2Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq)MASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Dec 10, 2019·11 cites·16 claims
- 3095US5925523AIntraction trap assay, reagents and uses thereofHARVARD COLLEGE·Filed 1997·Granted Jul 20, 1999·653 cites·36 claims
- 3194US11220678B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted Jan 11, 2022·2 cites·23 claims
- 3294US10479982B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Nov 19, 2019·5 cites·35 claims
- 3394US10011850B2Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome EditingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Jul 3, 2018·15 cites·14 claims
- 3493US10273271B2Methods of transcription activator like effector assemblyMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Apr 30, 2019·6 cites·14 claims
- 3593US9890364B2TAL-Tet1 fusion proteins and methods of use thereofMASSACHUSETTS GEN HOSPITAL·Filed 2013·Granted Feb 13, 2018·18 cites·10 claims
- 3693US7919610B2Yeast bacterial two-hybrid system and methods of use thereofFOX CHASE CANCER CT·Filed 2005·Granted Apr 5, 2011·27 cites·7 claims
- 3793US2025034597A1RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic LociMASSACHUSETTS GEN HOSPITAL·Filed 2024·Application pending·0 cites
- 3892US11060078B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted Jul 13, 2021·2 cites·29 claims
- 3992US10808233B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted Oct 20, 2020·3 cites·19 claims
- 4092US2024240207A1Increasing Specificity for RNA-Guided Genome EditingMASSACHUSETTS GEN HOSPITAL·Filed 2024·Application pending·0 cites
- 4191US10526589B2Multiplex guide RNAsMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Jan 7, 2020·8 cites·20 claims
- 4291US2024150741A1Engineered CRISPR-Cas9 nucleases with Altered PAM SpecificityMASSACHUSETTS GEN HOSPITAL·Filed 2023·Application pending·0 cites
- 4388US7029847B2Methods and compositions for interaction trap assaysMASSACHUSETTS INST TECHNOLOGY·Filed 2001·Granted Apr 18, 2006·17 cites·8 claims
- 4487US11286468B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Mar 29, 2022·2 cites·35 claims
- 4587US10676749B2Tale transcriptional activatorsMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Jun 9, 2020·2 cites·20 claims
- 4687US2023407341A1Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome EditingMASSACHUSETTS GEN HOSPITAL·Filed 2023·Application pending·0 cites
- 4786US10894950B2TAL-Tet1 fusion proteins and methods of use thereofMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jan 19, 2021·2 cites·14 claims
- 4886US2025115884A1TAL-Tet1 Fusion Proteins and Methods of Use ThereofMASSACHUSETTS GEN HOSPITAL·Filed 2024·Application pending·0 cites
- 4984US11667677B2Inducible, tunable, and multiplex human gene regulation using CRISPR-Cpf1MASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jun 6, 2023·3 cites·14 claims
- 5083US12404525B2Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cellsMASSACHUSETTS GEN HOSPITAL·Filed 2023·Granted Sep 2, 2025·0 cites·28 claims
Showing the top 50 of 109 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →