Inventor · disambiguated record
James L. Kirkland
Also filed as: KIRKLAND JAMES · KIRKLAND JAMES L
38 granted patents·15 pending applications·492 citations·filing 1967–2024
98Inventor score
Files withMAYO FOUND MEDICAL EDUCATION & RES14US NAVY14BUCK INST RES AGING11UNITY BIOTECHNOLOGY INC6KIRKLAND JAMES L2
Top patents by PatentIndex Score
53 records- 0198US10010546B2Treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2017·Granted Jul 3, 2018·23 cites·11 claims
- 0297US9968076B2Transgenic animals capable of being induced to delete senescent cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2015·Granted May 15, 2018·19 cites·31 claims
- 0397US9849128B2Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cellsBUCK INST RES AGING·Filed 2017·Granted Dec 26, 2017·24 cites·15 claims
- 0496US9993472B2Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2BUCK INST RES AGING·Filed 2015·Granted Jun 12, 2018·20 cites·7 claims
- 0596US9980962B2Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary diseaseBUCK INST RES AGING·Filed 2017·Granted May 29, 2018·6 cites·8 claims
- 0696US9855266B2Treatment for osteoarthritis by intra-articular administration of a cis-imidazolineBUCK INST RES AGING·Filed 2017·Granted Jan 2, 2018·12 cites·14 claims
- 0796US4021725AMobile mine detection system having plural color displayUS NAVY·Filed 1976·Granted May 3, 1977·82 cites·10 claims
- 0895US10328073B2Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Jun 25, 2019·9 cites·16 claims
- 0995US10130628B2Treatment of joint painUNITY BIOTECHNOLOGY INC·Filed 2017·Granted Nov 20, 2018·6 cites·8 claims
- 1094US10478432B2Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2018·Granted Nov 19, 2019·7 cites·18 claims
- 1193US4492111ARheological penetrometerKIRKLAND JAMES L·Filed 1981·Granted Jan 8, 1985·102 cites·13 claims
- 1292US10517866B2Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitorUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Dec 31, 2019·5 cites·15 claims
- 1392US10258618B2Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimenBUCK INST RES AGING·Filed 2018·Granted Apr 16, 2019·5 cites·17 claims
- 1491US10328058B2Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaquesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2017·Granted Jun 25, 2019·5 cites·12 claims
- 1591US10213426B2Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell populationBUCK INST RES AGING·Filed 2017·Granted Feb 26, 2019·5 cites·13 claims
- 1690US11351167B2Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2019·Granted Jun 7, 2022·1 cites·14 claims
- 1790US10478433B2Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision lossUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Nov 19, 2019·4 cites·20 claims
- 1890US10413542B2Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinaseBUCK INST RES AGING·Filed 2018·Granted Sep 17, 2019·4 cites·12 claims
- 1987US5019822AMarine object detectorUS NAVY·Filed 1973·Granted May 28, 1991·40 cites·4 claims
- 2082US11925640B2Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionalityMAYO FOUND MEDICAL EDUCATION & RES·Filed 2019·Granted Mar 12, 2024·1 cites·15 claims
- 2180US12226416B2Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionalityMAYO FOUND MEDICAL EDUCATION & RES·Filed 2024·Granted Feb 18, 2025·0 cites·16 claims
- 2279US11980616B2Treating liver disease by selectively eliminating senescent cellsBUCK INST RES AGING·Filed 2020·Granted May 14, 2024·0 cites·23 claims
- 2379US11517572B2Killing senescent cells and treating senescence-associated conditions using a SRC inhibitor and a flavonoidMAYO FOUND MEDICAL EDUCATION & RES·Filed 2020·Granted Dec 6, 2022·1 cites·3 claims
- 2479US2019343832A1Therapy for removing senescent cells and treating senescence-associated disease using an mdm2 inhibitorUNITY BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 2577US5007346ADevice for detecting and/or sweeping electrically controlled minesUS NAVY·Filed 1967·Granted Apr 16, 1991·18 cites·10 claims
- 2669US2023218617A1Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoidMAYO FOUND MEDICAL EDUCATION & RES·Filed 2022·Application pending·0 cites
- 2767US4992786AElectrical conductor detectorUS NAVY·Filed 1973·Granted Feb 12, 1991·14 cites·9 claims
- 2866US10251376B2Increasing healthy lifespan and delaying progression of age-related phenotypes by selectively removing senescent cellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Granted Apr 9, 2019·0 cites·12 claims
- 2965US2018279590A1Nucleic Acid Construct Comprising a P16 Promoter Controlling Expression of a Transgene that Causes Apoptosis in Senescent CellsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 3063US4970701AWire detectorUS NAVY·Filed 1971·Granted Nov 13, 1990·16 cites·15 claims
- 3162US2019022225A1Protocol for increasing life expectancy in a test subjectMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 3262US2025170129A1Senotherapeutic agents and alpha-klotho polypeptidesMAYO FOUND FOR MEDICAL EDUCATION AND RESEARC·Filed 2023·Application pending·0 cites
- 3361US2022386574A1P21-cre animal modelsMAYO FOUND MEDICAL EDUCATION & RES·Filed 2022·Application pending·0 cites
- 3458US2014189897A1Transgenic animals capable of being induced to delete senescent cellsKIRKLAND JAMES L·Filed 2012·Application pending·0 cites
- 3558US2019269675A1Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agentsBUCK INSTITUTE FOR RES AND AGING·Filed 2019·Application pending·0 cites
- 3656US2021379068A1Methods and materials for treating neuropsychiatric disordersMAYO FOUND MEDICAL EDUCATION & RES·Filed 2019·Application pending·0 cites
- 3754US3983750AFluid level sensing deviceUS NAVY·Filed 1975·Granted Oct 5, 1976·11 cites·11 claims
- 3852US5245588ARegenerative radio-frequency wire detectorUS NAVY·Filed 1972·Granted Sep 14, 1993·8 cites·19 claims
- 3952US4107607AMagnetometer using a field controlled oscillator, the oscillator core being maintained near its Curie pointUS NAVY·Filed 1977·Granted Aug 15, 1978·9 cites·4 claims
- 4052US2024016804A1Methods and materials for assessing and treating hypertensive disordersMAYO FOUND MEDICAL EDUCATION & RES·Filed 2020·Application pending·0 cites
- 4151US2017216286A1Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoidMAYO FOUNDATION·Filed 2015·Application pending·0 cites
- 4251US2018193458A1Compositions and methods for treating senescence-associated diseases and disordersUNITY BIOTECHNOLOGY INC·Filed 2016·Application pending·0 cites
- 4350US2021283185A1Methods and materials for improving transplant outcomesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2019·Application pending·0 cites
- 4449US2005008621A1Preadipocyte cell strains and uses thereforeFiled 2002·Application pending·0 cites
- 4549US2019000846A1Pharmaceutical Products and Drug Combinations for Treating Atherosclerosis by Stabilizing Atherosclerotic Plaques and Promoting Plaque RegressionMAYO FOUND MEDICAL EDUCATION & RES·Filed 2018·Application pending·0 cites
- 4648US4606293AExplosively actuated mine cable marker deviceUS NAVY·Filed 1985·Granted Aug 19, 1986·9 cites·7 claims
- 4746US4990852AAutomatic classifier for electric wire detectorUS NAVY·Filed 1973·Granted Feb 5, 1991·6 cites·10 claims
- 4844US4972388AElectrical cable markerUS OF AMERICAS AS REPRESENTED·Filed 1975·Granted Nov 20, 1990·7 cites·17 claims
- 4943US5249162ARadio frequency phase sensitive wire detectorUS NAVY·Filed 1973·Granted Sep 28, 1993·5 cites·12 claims
- 5038US4970702AElectrical conductor detecting deviceUS NAVY·Filed 1968·Granted Nov 13, 1990·2 cites·10 claims
Showing the top 50 of 53 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →