Inventor · disambiguated record
Jean-Michel Adam
Also filed as: ADAM JEAN-MICHEL
14 granted patents·19 pending applications·45 citations·filing 2002–2024
89Inventor score
Files withHOFFMANN LA ROCHE18ABRECHT STEFAN5ADAM JEAN-MICHEL3ISOTECHNIKA INC3AURINIA PHARMACEUTICALS INC1
Top patents by PatentIndex Score
33 records- 0190US11390632B2Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo [1,2-B]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivativesHOFFMANN LA ROCHE·Filed 2020·Granted Jul 19, 2022·3 cites·26 claims
- 0287US7141648B2Synthesis of cyclosporin analogsISOTECHNIKA INC·Filed 2002·Granted Nov 28, 2006·17 cites·5 claims
- 0385US9056866B2[1,2,3]triazolo[4,5-D]pyrimidine derivativesHOFFMANN LA ROCHE·Filed 2014·Granted Jun 16, 2015·7 cites·46 claims
- 0482US8741906B2[1,2,3]triazolo[4,5-D]pyrimidine derivativesHOFFMANN LA ROCHE·Filed 2012·Granted Jun 3, 2014·5 cites·30 claims
- 0582US7619101B2Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one useful in the preparation of the DPP-IV inhibitor (S)-1 ((2S,3S,11bS)-2-amino-9,10-dimethoxy-1,3,4,6,7, 11b-hexahydro-2H-pyrido[2,1-a] isoquinolin-3-yl)-4-fluoromethyl-pyrrolidin-2-oneHOFFMANN LA ROCHE·Filed 2006·Granted Nov 17, 2009·4 cites·21 claims
- 0677US11040977B2Synthesis of trans-8-chloro-5-methyl-1-[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[e]azulene and crytalline forms thereofHOFFMANN LA ROCHE·Filed 2019·Granted Jun 22, 2021·1 cites·2 claims
- 0777US10246460B2Synthesis of trans-8-chloro-5-methyl-1-[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[E]azulene and crytalline forms thereofHOFFMANN LA ROCHE·Filed 2016·Granted Apr 2, 2019·2 cites·6 claims
- 0877US9527810B2(3,4-dichloro-phenyl)-((S)-3-propyl-pyrrolidin-3-yl)-methanone hydrochloride and manufacturing processesHOFFMANN LA ROCHE·Filed 2014·Granted Dec 27, 2016·4 cites·11 claims
- 0977US2025084102A1Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivativesHOFFMANN LA ROCHE·Filed 2024·Application pending·0 cites
- 1076US12122791B2Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8- dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivativesHOFFMANN LA ROCHE·Filed 2022·Granted Oct 22, 2024·0 cites·10 claims
- 1170US12459947B2Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[e]azulene and crystalline forms thereofHOFFMANN LA ROCHE·Filed 2021·Granted Nov 4, 2025·0 cites·2 claims
- 1269US2010062976A1Synthesis of Cyclosporin AnalogsISOTECHNIKA INC·Filed 2009·Application pending·0 cites
- 1366US2025109166A1Process for manufacturing macrocyclic peptidesHOFFMANN LA ROCHE·Filed 2024·Application pending·0 cites
- 1465US8420818B2Process for the preparation of pyrido[2,1-a] isoquinoline derivativesABRECHT STEFAN·Filed 2011·Granted Apr 16, 2013·2 cites·16 claims
- 1562US2013338366A1Process for the preparation of pyrido [2,1-a] isoquinoline derivatives comprising optical resolution of an enamineHOFFMANN LA ROCHE·Filed 2013·Application pending·0 cites
- 1662US2024287084A1Synthesis of [1,2,3]triazolo[4,5-d]pyrimidinesHOFFMANN LA ROCHE·Filed 2024·Application pending·0 cites
- 1761US2024182493A1ProcessHOFFMANN LA ROCHE·Filed 2023·Application pending·0 cites
- 1861US2007087963A1Synthesis of cyclosporin analogsNAICKER SELVARAJ A·Filed 2006·Application pending·0 cites
- 1960US2024309013A1SYNTHESIS OF 2'-(7,7-dimethyl-1'H,7H-spiro[furo[3,4-b]pyridine-5,4'-piperidin]-1'-yl)-1,3-dihydro-4'H-spiro[indene-2,5'-[1,3]oxazol]-4'-oneHOFFMANN LA ROCHE·Filed 2024·Application pending·0 cites
- 2057US2008071087A1PROCESS FOR THE PREPARATION OF PYRIDO [2,1-a] ISOQUINOLINE DERIVATIVES COMPRISING OPTICAL RESOLUTION OF AN ENAMINEABRECHT STEFAN·Filed 2007·Application pending·0 cites
- 2157US2025326759A1Process for preparing 1-[5-tert-butyl-3-[(1-methyltetrazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-yl]pyrrolidin-3-olHOFFMANN LA ROCHE·Filed 2024·Application pending·0 cites
- 2255US7872141B2Processes for the manufacture of a pyrrolidine-3,4-dicarboxamide derivativeHOFFMANN LA ROCHE·Filed 2007·Granted Jan 18, 2011·0 cites·8 claims
- 2355US2009163718A1PROCESS FOR THE PREPARATION OF PYRIDO[2,1-a] ISOQUINOLINE DERIVATIVESABRECHT STEFAN·Filed 2008·Application pending·0 cites
- 2454US2013018191A1Process for the preparation of pyrido [2,1-a] isoquinoline derivatives comprising optical resolution of an enamineABRECHT STEFAN·Filed 2012·Application pending·0 cites
- 2552US2015126743A1Process For The Preparation Of Pyrido [2,1-A] Isoquinoline Derivatives Comprising Optical Resolution Of An EnamineHOFFMANN LA ROCHE·Filed 2015·Application pending·0 cites
- 2652US2012022260A1PROCESS FOR THE PREPARATION OF PYRIDO [2,1-a] ISOQUINOLINE DERIVATIVES COMPRISING OPTICAL RESOLUTION OF AN ENAMINEABRECHT STEFAN·Filed 2011·Application pending·0 cites
- 2749US2014288266A1Synthesis of Cyclosporin AnalogsAURINIA PHARMACEUTICALS INC·Filed 2014·Application pending·0 cites
- 2847US8138175B2Heterocyclyl compoundsADAM JEAN-MICHEL·Filed 2009·Granted Mar 20, 2012·0 cites·23 claims
- 2946US8227613B2Heteroaryl carboxamide derivativesADAM JEAN-MICHEL·Filed 2009·Granted Jul 24, 2012·0 cites·21 claims
- 3043US2011092669A1Synthesis of cyclosporin analogsISOTECHNIKA INC·Filed 2010·Application pending·0 cites
- 3140US2009215826A1Solid forms of a pyrrolidine-3,4-dicarboxamide derivativeADAM JEAN-MICHEL·Filed 2009·Application pending·0 cites
- 3239US2004220091A1Process for preparation of cyclosporin A analogsFiled 2004·Application pending·0 cites
- 3338US2019315669A1Process for the preparation of hu-910 and crystalline structure thereofYISSUM RESEARCH DEVELOPEMENT COMPANY OF THE HEBREW UNIV OF JERUSALEM LTD·Filed 2017·Application pending·0 cites
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →