Inventor · disambiguated record
Phillip Dan Cook
Also filed as: COOK PHILLIP D · COOK PHILLIP DAN · COOK PHILLIP MICHAEL
190 granted patents·34 pending applications·42,980 citations·filing 1983–2017
99Inventor score
Files withISIS PHARMACEUTICALS INC184WARNER LAMBERT CO6BHAT BALKRISHEN5BIOTA SCIENT MANAGEMENT5MERCK & CO INC3
Top patents by PatentIndex Score
224 records- 0199USRE39464EOligonucleolotides having site specific chiral phosphorothioate internucleoside linkagesISIS PHARMACEUTICALS INC·Filed 2004·Granted Jan 9, 2007·235 cites·64 claims
- 0299US7015315B1Gapped oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1995·Granted Mar 21, 2006·409 cites·30 claims
- 0399US6600032B12′-O-aminoethyloxyethyl-modified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1999·Granted Jul 29, 2003·338 cites·31 claims
- 0499US6531584B12'modified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1999·Granted Mar 11, 2003·407 cites·5 claims
- 0599US6239265B1Oligonucleotides having chiral phosphorus linkagesISIS PHARMACEUTICALS INC·Filed 1998·Granted May 29, 2001·471 cites·10 claims
- 0699US5681941ASubstituted purines and oligonucleotide cross-linkingISIS PHARMACEUTICALS INC·Filed 1994·Granted Oct 28, 1997·1.4k cites·79 claims
- 0799US5677437AHeteroatomic oligonucleoside linkagesISIS PHARMACEUTICALS INC·Filed 1995·Granted Oct 14, 1997·1.3k cites·29 claims
- 0899US5637684APhosphoramidate and phosphorothioamidate oligomeric compoundsISIS PHARMACEUTICALS INC·Filed 1994·Granted Jun 10, 1997·561 cites·21 claims
- 0999US5623070AHeteroatomic oligonucleoside linkagesISIS PHARMACEUTICALS INC·Filed 1995·Granted Apr 22, 1997·1.4k cites·8 claims
- 1099US5587469AOligonucleotides containing N-2 substituted purinesISIS PHARMACEUTICALS INC·Filed 1995·Granted Dec 24, 1996·1.4k cites·29 claims
- 1199US5587361AOligonucleotides having phosphorothioate linkages of high chiral purityISIS PHARMACEUTICALS INC·Filed 1995·Granted Dec 24, 1996·1.4k cites·18 claims
- 1299US5578718AThiol-derivatized nucleosidesISIS PHARMACEUTICALS INC·Filed 1993·Granted Nov 26, 1996·1k cites·25 claims
- 1399US5539083APeptide nucleic acid combinatorial libraries and improved methods of synthesisISIS PHARMACEUTICALS INC·Filed 1994·Granted Jul 23, 1996·782 cites·67 claims
- 1499US5489677AOligonucleoside linkages containing adjacent oxygen and nitrogen atomsISIS PHARMACEUTICALS INC·Filed 1993·Granted Feb 6, 1996·1.8k cites·16 claims
- 1599US5359044ACyclobutyl oligonucleotide surrogatesISIS PHARMACEUTICALS INC·Filed 1991·Granted Oct 25, 1994·1.2k cites·13 claims
- 1698US7202224B2Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymeraseISIS PHARMACEUTICALS INC·Filed 2006·Granted Apr 10, 2007·222 cites·1 claims
- 1798US7125855B2Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymeraseMERCK & CO INC·Filed 2003·Granted Oct 24, 2006·301 cites·4 claims
- 1898US7105499B2Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymeraseISIS PHARMACEUTICALS INC·Filed 2002·Granted Sep 12, 2006·233 cites·2 claims
- 1998US6861514B2Nucleosidic and non-nucleosidic folate conjugatesISIS PHARMACEUTICALS INC·Filed 2001·Granted Mar 1, 2005·122 cites·33 claims
- 2098US6777395B2Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase of hepatitis C virusMERCK & CO INC·Filed 2002·Granted Aug 17, 2004·356 cites·13 claims
- 2198US6747014B2Compositions and methods for non-parenteral delivery of oligonucleotidesISIS PHARMACEUTICALS INC·Filed 2001·Granted Jun 8, 2004·356 cites·10 claims
- 2298US6639062B2Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefromISIS PHARMACEUTICALS INC·Filed 1999·Granted Oct 28, 2003·259 cites·83 claims
- 2398US6534639B1Guanidinium functionalized oligonucleotides and method/synthesisISIS PHARMACEUTICALS INC·Filed 2000·Granted Mar 18, 2003·261 cites·26 claims
- 2498US6528631B1Oligonucleotide-folate conjugatesISIS PHARMACEUTICALS INC·Filed 1998·Granted Mar 4, 2003·461 cites·42 claims
- 2598US6395492B1Derivatized oligonucleotides having improved uptake and other propertiesISIS PHARMACEUTICALS INC·Filed 2000·Granted May 28, 2002·234 cites·9 claims
- 2698US6335434B1Nucleosidic and non-nucleosidic folate conjugatesISIS PHARMACEUTICALS INC·Filed 1999·Granted Jan 1, 2002·558 cites·4 claims
- 2798US6326199B1Gapped 2′ modified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1999·Granted Dec 4, 2001·282 cites·20 claims
- 2898US6005087A2'-modified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1998·Granted Dec 21, 1999·449 cites·3 claims
- 2998US5859221A2'-modified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1995·Granted Jan 12, 1999·449 cites·6 claims
- 3098US5688941AMethods of making conjugated 4' desmethyl nucleoside analog compoundsISIS PHARMACEUTICALS INC·Filed 1996·Granted Nov 18, 1997·804 cites·5 claims
- 3198US5670633ASugar modified oligonucleotides that detect and modulate gene expressionISIS PHARMACEUTICALS INC·Filed 1991·Granted Sep 23, 1997·1.5k cites·3 claims
- 3298US5661134AOligonucleotides for modulating Ha-ras or Ki-ras having phosphorothioate linkages of high chiral purityISIS PHARMACEUTICALS INC·Filed 1995·Granted Aug 26, 1997·249 cites·18 claims
- 3398US5623065AGapped 2' modified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1992·Granted Apr 22, 1997·662 cites·19 claims
- 3498US5618704ABackbone-modified oligonucleotide analogs and preparation thereof through radical couplingISIS PHARMACUETICALS INC·Filed 1994·Granted Apr 8, 1997·1.3k cites·10 claims
- 3598US5610289ABackbone modified oligonucleotide analoguesISIS PHARMACEUTICALS INC·Filed 1992·Granted Mar 11, 1997·1.6k cites·29 claims
- 3698US5608046AConjugated 4'-desmethyl nucleoside analog compoundsISIS PHARMACEUTICALS INC·Filed 1994·Granted Mar 4, 1997·1.7k cites·30 claims
- 3798US5212295AMonomers for preparation of oligonucleotides having chiral phosphorus linkagesISIS PHARMACEUTICALS INC·Filed 1991·Granted May 18, 1993·389 cites·9 claims
- 3897US8691785B2Compositions and methods for non-parenteral delivery of oligonucleotidesISIS PHARMACEUTICALS INC·Filed 2013·Granted Apr 8, 2014·48 cites·13 claims
- 3997US7268119B2Tricyclic nucleosides or nucleotides as therapeutic agentsBIOTA SCIENT MANAGEMENT·Filed 2007·Granted Sep 11, 2007·138 cites·19 claims
- 4097US6753423B1Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammalsISIS PHARMACEUTICALS INC·Filed 2000·Granted Jun 22, 2004·88 cites·7 claims
- 4197US6222025B1Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefromISIS PHARMACEUTICALS INC·Filed 1996·Granted Apr 24, 2001·342 cites·33 claims
- 4297US6166197AOligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutionsISIS PHARMACEUTICALS INC·Filed 1995·Granted Dec 26, 2000·417 cites·3 claims
- 4397US5576302AOligonucleotides for modulating hepatitis C virus having phosphorothioate linkages of high chiral purityISIS PHARMACEUTICALS INC·Filed 1995·Granted Nov 19, 1996·255 cites·30 claims
- 4497US5521302AProcess for preparing oligonucleotides having chiral phosphorus linkagesISIS PHARMACEUTICALS INC·Filed 1993·Granted May 28, 1996·243 cites·12 claims
- 4597US5386023ABackbone modified oligonucleotide analogs and preparation thereof through reductive couplingISIS PHARMACEUTICALS INC·Filed 1993·Granted Jan 31, 1995·1k cites·20 claims
- 4696US7807653B2Nucleotide mimics and their prodrugsBIOTA SCIENT MANAGEMENT·Filed 2007·Granted Oct 5, 2010·86 cites·28 claims
- 4796US6172209B1Aminooxy-modified oligonucleotides and methods for making sameISIS PHARMACEUTICALS INC·Filed 1998·Granted Jan 9, 2001·378 cites·37 claims
- 4896US6147200A2'-O-acetamido modified monomers and oligomersISIS PHARMACEUTICALS INC·Filed 1999·Granted Nov 14, 2000·466 cites·46 claims
- 4996US5808023AModified oligonucleotidesISIS PHARMACEUTICALS INC·Filed 1994·Granted Sep 15, 1998·87 cites·20 claims
- 5096US5700922APNA-DNA-PNA chimeric macromoleculesISIS PHARMACEUTICALS INC·Filed 1993·Granted Dec 23, 1997·810 cites·23 claims
Showing the top 50 of 224 patent records by PatentIndex Score.
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