Inventor · disambiguated record
Xandra O. Breakefield
Also filed as: BREAKEFIELD XANDRA · BREAKEFIELD XANDRA O
31 granted patents·25 pending applications·544 citations·filing 1987–2024
97Inventor score
Files withGEN HOSPITAL CORP27MASSACHUSETTS GEN HOSPITAL17CHILDRENS MEDICAL CENTER3UNIV NORTHEASTERN OHIO3CHEN WALTER1
Top patents by PatentIndex Score
56 records- 0188US5501979AHerpes simplex virus type I expression vectorGEN HOSPITAL CORP·Filed 1993·Granted Mar 26, 1996·138 cites·13 claims
- 0287US10793914B2Cancer-related biological materials in microvesiclesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Oct 6, 2020·3 cites·6 claims
- 0387US9829483B2Methods of isolating extracellular vesiclesMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Nov 28, 2017·7 cites·16 claims
- 0487US7186409B2Neural stem cells and use thereof for brain tumor therapyUNIV NORTHEASTERN OHIO·Filed 2001·Granted Mar 6, 2007·21 cites·1 claims
- 0586US7655224B2Neural stem cells and use thereof for brain tumor therapyCHILDRENS MEDICAL CENTER·Filed 2006·Granted Feb 2, 2010·8 cites·5 claims
- 0686US5688773AMethod of selectively destroying neoplastic cellsGEN HOSPITAL CORP·Filed 1994·Granted Nov 18, 1997·78 cites·27 claims
- 0784US9644215B2AAV1-caspase gene therapy induced pyroptosis for the treatment of tumorsMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted May 9, 2017·6 cites·20 claims
- 0881US6677155B1Triple hybrid amplicon vector systems to generate retroviral packaging linesGEN HOSPITAL CORP·Filed 2000·Granted Jan 13, 2004·17 cites·30 claims
- 0979US6673602B1Herpes simplex virus amplicon vector targeting system and method of using sameGEN HOSPITAL CORP·Filed 2000·Granted Jan 6, 2004·13 cites·40 claims
- 1078US11866783B2Extracellular mRNA markers of muscular dystrophies in human urineMASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Jan 9, 2024·1 cites·3 claims
- 1178US6770632B1Folypolyglutamyl synthetase gene transfer to enhance antifolateGEN HOSPITAL CORP·Filed 2000·Granted Aug 3, 2004·18 cites·21 claims
- 1277US4948590AAvidin or streptavidin conjugated liposomesUNIV YALE·Filed 1987·Granted Aug 14, 1990·44 cites·12 claims
- 1373US10407728B2Use of microvesicles in analyzing nucleic acid profilesMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted Sep 10, 2019·1 cites·7 claims
- 1472US2024084388A1Extracellular mRNA Markers of Muscular Dystrophies in Human UrineMASSACHUSETTS GEN HOSPITAL·Filed 2023·Application pending·0 cites
- 1571US7393526B2Systemic gene delivery vehicles for the treatment of tumorsCHILDRENS MEDICAL CENTER·Filed 2001·Granted Jul 1, 2008·5 cites·11 claims
- 1671US6573090B1Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectorsGEN HOSPITAL CORP·Filed 1999·Granted Jun 3, 2003·44 cites·29 claims
- 1769US11519036B2Use of microvesicles in analyzing nucleic acid profilesMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted Dec 6, 2022·0 cites·7 claims
- 1868US5407821AGenetic diagnosis of torsion dystoniaGEN HOSPITAL CORP·Filed 1991·Granted Apr 18, 1995·23 cites·23 claims
- 1968US2024343768A1Gene therapy for tuberous sclerosisMASSACHUSETTS GEN HOSPITAL·Filed 2024·Application pending·0 cites
- 2067US2011053157A1Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditionsGEN HOSPITAL CORP·Filed 2009·Application pending·0 cites
- 2166US2020399714A1Cancer-related biological materials in microvesiclesMASSACHUSETTS GEN HOSPITAL·Filed 2020·Application pending·0 cites
- 2265US6387616B1Torsin, torsin genes, and methods of useGEN HOSPITAL CORP·Filed 1998·Granted May 14, 2002·21 cites·26 claims
- 2364US2014194319A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsGEN HOSPITAL CORP·Filed 2014·Application pending·0 cites
- 2463US6610287B1Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replicationGEN HOSPITAL CORP·Filed 1994·Granted Aug 26, 2003·26 cites·12 claims
- 2563US2017314075A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsMASSACHUSETTS GEN HOSPITAL·Filed 2017·Application pending·0 cites
- 2662US2008152590A1Engraftable Neural Progenitor and Stem Cells for Brain Tumor TherapyCHILDRENS MEDICAL CENTER·Filed 2008·Application pending·0 cites
- 2762US2005169897A1Engraftable neural progenitor and stem cells for brain tumor therapyUNIV NORTHEASTERN OHIO·Filed 2004·Application pending·0 cites
- 2862US2014194613A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsGEN HOSPITAL CORP·Filed 2013·Application pending·0 cites
- 2961US2013131194A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsGEN HOSPITAL CORP·Filed 2012·Application pending·0 cites
- 3061US2018051335A9Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsMASSACHUSETTS GEN HOSPITAL·Filed 2016·Application pending·0 cites
- 3160US2024183842A1Supercharged Biovesicles and Methods of Use ThereofMASSACHUSETTS GEN HOSPITAL·Filed 2022·Application pending·0 cites
- 3260US2022162704A1Methods of preparing microvesicle micrornas from bodily fluidsMASSACHUSETTS GEN HOSPITAL·Filed 2022·Application pending·0 cites
- 3358US2016362678A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsMASSACHUSETTS GEN HOSPITAL·Filed 2015·Application pending·0 cites
- 3457US11958887B2Gene therapy for tuberous sclerosisMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Apr 16, 2024·0 cites·21 claims
- 3557US2014045915A1Cancer-related biological materials in microvesiclesSKOG JOHAN KARL OLOV·Filed 2011·Application pending·0 cites
- 3656US5965441AHSV/AAV hybrid amplicon vectorsGEN HOSPITAL COPORATION·Filed 1997·Granted Oct 12, 1999·19 cites·10 claims
- 3755US11155874B2Use of microvesicles in analyzing mutationsMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted Oct 26, 2021·0 cites·37 claims
- 3855US6921814B2Torsin, torsin-related genes and methods of detecting neuronal diseaseGEN HOSPITAL CORP·Filed 2001·Granted Jul 26, 2005·1 cites·4 claims
- 3955US2011003704A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsGEN HOSPITAL CORP·Filed 2010·Application pending·0 cites
- 4054US2013029339A1Use of microvesicles in analyzing kras mutationsGEN HOSPITAL CORP·Filed 2010·Application pending·0 cites
- 4154US2010196426A1Use of microvesicles in diagnosis and prognosis of medical diseases and conditionsGEN HOSPITAL CORP·Filed 2010·Application pending·0 cites
- 4253US2002115213A1Engraftable neural progenitor & stem cells for brain tumor therapyUNIV NORTHEASTERN OHIO·Filed 2001·Application pending·0 cites
- 4352US2016201121A1Microvesicle-based assaysGEN HOSPITAL CORP·Filed 2015·Application pending·0 cites
- 4450US5998133AUse of genetic markers to diagnose familial dysautonomiaGEN HOSPITAL CORP·Filed 1995·Granted Dec 7, 1999·8 cites·9 claims
- 4550US2014147839A1Microvesicle-based assaysCHEN WALTER·Filed 2011·Application pending·0 cites
- 4646US5783680AGenetic diagnosis and treatment for impulsive aggressionGEN HOSPITAL CORP·Filed 1993·Granted Jul 21, 1998·12 cites·10 claims
- 4744US6602499B1Combination viral-based and gene-based therapy of tumorsGEN HOSPITAL CORP·Filed 1999·Granted Aug 5, 2003·8 cites·30 claims
- 4843US2013040833A1Use of microvesicles in analyzing nucleic acid profilesGEN HOSPITAL CORP·Filed 2010·Application pending·0 cites
- 4942US6555108B1Implanting HSV-TK retrovirus producing cells to treat tumorsGEN HOSPITAL CORP·Filed 1995·Granted Apr 29, 2003·5 cites·9 claims
- 5042US2010035287A1Secreted Luciferase Fluorescent Protein Conjugate Nucleic Acid Construct and Uses ThereofGEN HOSPITAL CORP·Filed 2007·Application pending·0 cites
Showing the top 50 of 56 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →