Inventor · disambiguated record
Yi Zhu
Also filed as: ZHU YI · ZHU YI ZHUN
38 granted patents·36 pending applications·171 citations·filing 2006–2023
97Inventor score
Files withSYSTIMMUNE INC30BUCK INST RES AGING11UNITY BIOTECHNOLOGY INC6MAYO FOUND MEDICAL EDUCATION & RES4SICHUAN BAILI PHARMACEUTICAL CO LTD4
Top patents by PatentIndex Score
74 records- 0198US10010546B2Treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2017·Granted Jul 3, 2018·23 cites·11 claims
- 0297US9849128B2Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cellsBUCK INST RES AGING·Filed 2017·Granted Dec 26, 2017·24 cites·15 claims
- 0396US9993472B2Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2BUCK INST RES AGING·Filed 2015·Granted Jun 12, 2018·20 cites·7 claims
- 0496US9980962B2Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary diseaseBUCK INST RES AGING·Filed 2017·Granted May 29, 2018·6 cites·8 claims
- 0596US9855266B2Treatment for osteoarthritis by intra-articular administration of a cis-imidazolineBUCK INST RES AGING·Filed 2017·Granted Jan 2, 2018·12 cites·14 claims
- 0695US10328073B2Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Jun 25, 2019·9 cites·16 claims
- 0795US10130628B2Treatment of joint painUNITY BIOTECHNOLOGY INC·Filed 2017·Granted Nov 20, 2018·6 cites·8 claims
- 0894US10478432B2Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2018·Granted Nov 19, 2019·7 cites·18 claims
- 0992US10517866B2Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitorUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Dec 31, 2019·5 cites·15 claims
- 1092US10258618B2Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimenBUCK INST RES AGING·Filed 2018·Granted Apr 16, 2019·5 cites·17 claims
- 1191US10328058B2Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaquesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2017·Granted Jun 25, 2019·5 cites·12 claims
- 1291US10213426B2Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell populationBUCK INST RES AGING·Filed 2017·Granted Feb 26, 2019·5 cites·13 claims
- 1390US12029761B2Guidance and Navigation Control proteins and method of making and using thereofSYSTIMMUNE INC·Filed 2019·Granted Jul 9, 2024·6 cites·21 claims
- 1490US11351167B2Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2019·Granted Jun 7, 2022·1 cites·14 claims
- 1590US10478433B2Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision lossUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Nov 19, 2019·4 cites·20 claims
- 1690US10413542B2Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinaseBUCK INST RES AGING·Filed 2018·Granted Sep 17, 2019·4 cites·12 claims
- 1788US11787863B2Multi-specific antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted Oct 17, 2023·6 cites·16 claims
- 1887US10919977B2Bispecific tetravalent antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2015·Granted Feb 16, 2021·6 cites·29 claims
- 1984US11439608B2Roles of modulators of intersectin-CDC42 signaling in Alzheimer's diseaseLU QUN·Filed 2018·Granted Sep 13, 2022·2 cites·4 claims
- 2079US11980616B2Treating liver disease by selectively eliminating senescent cellsBUCK INST RES AGING·Filed 2020·Granted May 14, 2024·0 cites·23 claims
- 2179US11517572B2Killing senescent cells and treating senescence-associated conditions using a SRC inhibitor and a flavonoidMAYO FOUND MEDICAL EDUCATION & RES·Filed 2020·Granted Dec 6, 2022·1 cites·3 claims
- 2279US2019343832A1Therapy for removing senescent cells and treating senescence-associated disease using an mdm2 inhibitorUNITY BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 2378US12384850B2Guidance and navigation control proteins and method of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted Aug 12, 2025·1 cites·13 claims
- 2478US11518815B2Anti-ROR1 antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted Dec 6, 2022·1 cites·11 claims
- 2577US12285393B2Roles of modulators of intersectin-Cdc42 signaling in Alzheimer's diseaseLU QUN·Filed 2022·Granted Apr 29, 2025·0 cites·1 claims
- 2677US8501762B2Tetrahydroprotoberberine compounds, the synthetic method and the use thereofLI JIANFENG·Filed 2006·Granted Aug 6, 2013·9 cites·8 claims
- 2773US11560431B2Anti-PD-L1 antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted Jan 24, 2023·1 cites·16 claims
- 2872US8871777B2Phenylpyrimidone compounds, the pharmaceutical compositions, preparation methods and uses thereofLIU ZHENG·Filed 2009·Granted Oct 28, 2014·2 cites·14 claims
- 2972US2025376531A9Anti-4-1bb antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2023·Application pending·0 cites
- 3069US2023218617A1Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoidMAYO FOUND MEDICAL EDUCATION & RES·Filed 2022·Application pending·0 cites
- 3169US2023322920A1Multi-specific antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2023·Application pending·0 cites
- 3264US2024279333A1Multi-specific antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2023·Application pending·0 cites
- 3362US11987635B2Anti-4-1BB antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted May 21, 2024·0 cites·6 claims
- 3462US2025170129A1Senotherapeutic agents and alpha-klotho polypeptidesMAYO FOUND FOR MEDICAL EDUCATION AND RESEARC·Filed 2023·Application pending·0 cites
- 3560US2025059296A1Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereofSYSTIMMUNE INC·Filed 2022·Application pending·0 cites
- 3659US12428483B2Bispecific tetravalent antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2021·Granted Sep 30, 2025·0 cites·14 claims
- 3759US2025353917A1Egfr binding complex and method of making and using thereofSYSTIMMUNE INC·Filed 2021·Application pending·0 cites
- 3858US2019269675A1Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agentsBUCK INSTITUTE FOR RES AND AGING·Filed 2019·Application pending·0 cites
- 3958US2023374157A1Specificy-enhanced bispecific antibody (seba)SYSTIMMUNE INC·Filed 2021·Application pending·0 cites
- 4057US2024309099A1Bispecific tetravalent antibody targeting egfr and her3SYSTIMMUNE INC·Filed 2022·Application pending·0 cites
- 4156US11649286B2Tri-specific antibodiesSYSTIMMUNE INC·Filed 2018·Granted May 16, 2023·0 cites·17 claims
- 4256US8071765B2Process for the preparation of sildenafil and intermediates thereofTIAN GUANGHUI·Filed 2006·Granted Dec 6, 2011·0 cites·9 claims
- 4355US2025270566A1Dual-specificity rna atpamers for regulating o-glcnacylationUNIV GEORGIA·Filed 2022·Application pending·0 cites
- 4455US2023114801A1MINIATURE GUIDANCE AND NAVIGATION CONTROL (miniGNC) ANTIBODY-LIKE PROTEINS AND METHODS OF MAKING AND USING THEREOFSYSTIMMUNE INC·Filed 2021·Application pending·0 cites
- 4555US2023113563A1Guidance and navigation control (gnc) antibody-like proteinsand methods of making and using thereofSYSTIMMUNE INC·Filed 2021·Application pending·0 cites
- 4655US2025295797A1Ligand-drug conjugate containing hydrophilic sugar structureSYSTIMMUNE INC·Filed 2023·Application pending·0 cites
- 4755US2024398943A1Methods of treating cancer and the pharmaceutical compositions thereofSYSTIMMUNE INC·Filed 2022·Application pending·0 cites
- 4854US11535667B2Anti-CD3 antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted Dec 27, 2022·0 cites·17 claims
- 4953US11466084B2Anti-PD-1 antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2018·Granted Oct 11, 2022·0 cites·16 claims
- 5053US10717783B2Bispecific tetravalent antibodies and methods of making and using thereofSYSTIMMUNE INC·Filed 2015·Granted Jul 21, 2020·0 cites·18 claims
Showing the top 50 of 74 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →