α-amino acrylate microbicide, and preparation method therefor and uses thereof

Abstract

The present invention relates to a microbicidal α-amino acrylic derivative and its preparation method and applications. Based on the principle of pesticide molecular design, the structural reform of the agricultural anti-plant virus activity is carried on lead compounds having the medical anti-coronavirus activity, and a series of α-amino acrylic derivatives are designed and synthesized, and in particular, α-amino acrylic derivatives containing piperidine rings are synthesized, and the systematic biological activity screening is carried by using known compounds as positive control compounds, which provide many effective anti-virus leading molecules for the preparation of pesticides, and has positive significance to reduce the pesticide application dosage and protect the environment and ecology.

What is claimed is: 
     
       1. A α-amino acrylic derivative with a formula of 
       
         
           
           
               
               
           
         
       
       wherein:
 R 1  is cyclopropyl or cyclohexyl, 
 R 2  is phenyl, 
 XR 3  is [4-(4-bromobenzene)-4-hydroxy]-1-piperidinyl.