US2005096287A1PendingUtilityA1

Compositions and methods for topical delivery of oligonucleotides

Priority: May 21, 1998Filed: Jun 25, 2004Published: May 5, 2005

Est. expiryMay 21, 2018(expired)· nominal 20-yr term from priority

Inventors:Rahul Mehta Gregory E. Hardee Phillip Dan Cook David J. Ecker Yali Jennifer Tsai Michael V. Templin

A61K 48/0075A61K 48/0041A61P 37/00A61K 48/0025A61P 31/00A61P 35/00A61K 48/0008

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Claims

Abstract

The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes.

Claims

exact text as granted — not AI-modified

1 . A pharmaceutical composition comprising an oligonucleotide admixed with a topical delivery agent.

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