US4146722AExpiredUtility

Imidazo[1,5-a][1,4]benzodiazepines

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Assignee: HOFFMANN LA ROCHEPriority: Mar 11, 1977Filed: Jul 27, 1978Granted: Mar 27, 1979
Est. expiryMar 11, 1997(expired)· nominal 20-yr term from priority
A61P 25/20A61P 25/26A61P 21/02C07D 243/16C07D 487/04
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PatentIndex Score
1
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2
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1
Claims

Abstract

Compounds are disclosed of the formula ##STR1## wherein R 1 is hydrogen, halogen or trifluoromethyl; R 2 is selected from the group consisting of lower alkylthio together with the sulfoxide and sulfone thereof, halo, lower alkylamino or lower alkoxy; Y is oxo or thio; R 3 is selected from the group consisting of hydrogen, --COOR 4 wherein R 4 is hydrogen or lower alkyl, --CONR 6 R 5 wherein R 5 and R 6 are hydrogen or lower alkyl; X is hydrogen or halogen; and R 7 is lower alkyl or hydrogen and the pharmaceutically acceptable salts and N-oxides thereof. Also presented are processes to produce the above compounds and intermediates therefor and derivatives thereof.

Claims

exact text as granted — not AI-modified
We claim: 
     
       1. A compound of the formula ##STR8## wherein R 1  is hydrogen, halogen or trifluoromethyl; Y is oxo or thio; and X is hydrogen or halogen.

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