Phenoxypropanolamines

Abstract

[p-[2-[[(S)-2-hydroxy-3-phenoxypropyl]amino]-ethyl]phenoxy]acetic acid and its physiologically compatible salts, which have catabolic activity and can be used for the treatment of obesity, of diabetes and of conditions which are associated with increased protein breakdown or as feed additives for fattening animals, as described. The compounds are prepared starting from esters corresponding to the aforementioned acid.

We claim: 
     
       1. [p-[2-[[(S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenoxy]acetic acid or a physiologically compatible salt thereof. 
     
     
       2. The compound in accordance with claim 1, [p-[2-[[(S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenoxy]acetic acid hydrochloride. 
     
     
       3. The compound in accordance with claim 1, (p-[2-[[(S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenoxy]acetic acid. 
     
     
       4. A pharmaceutical composition comprising an effective amount of [p-[2-[[(S)-2-hydroxy-3-phenoxypropyl)amino]ethyl)phenoxy]acetic acid or a physiologically compatible salt thereof, and an inert carrier material. 
     
     
       5. A method of treating obesity, diabetes mellitus and conditions associated with an increased protein breakdown which comprises administering a therapeutically effective amount of [p-[2-[[(S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenoxy]acetic acid or a physiologically compatible salt thereof.