P
US5470565AExpiredUtilityPatentIndex 88

Composition for strengthening acid resistancy of teeth

Assignee: MITSUI NORIN KKPriority: Apr 19, 1993Filed: Mar 21, 1994Granted: Nov 28, 1995
Est. expiryApr 19, 2013(expired)· nominal 20-yr term from priority
Inventors:HAYAKAWA FUMIKOANDO TAKASHIKIMURA TAKAHIDEHARA YUKIHIKO
A61P 1/02A61Q 11/00A61K 8/9789A61K 8/27A61K 8/21A61K 8/498
88
PatentIndex Score
27
Cited by
23
References
16
Claims

Abstract

A composition is provided for strengthening the acid resistancy of teeth containing at least one tea polyphenol, a fluoride such as fluorosodium and an aluminum salt, such as aluminum lactate or aluminum nitrate.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A composition in the form of a toothpaste, a tooth powder or a mouthwash for strengthening acid resistancy of teeth consisting essentially of at least one tea polyphenol, a fluoride and an aluminum salt selected from the group consisting of aluminum nitrate, aluminum sulfate and aluminum lactate. 
     
     
       2. The composition according to claim 1, wherein the at least one tea polyphenol is contained in a concentration of 10-2,000 ppm, the fluoride is contained in a concentration of 20-1,000 ppm and the aluminum salt is contained in a concentration of 50-2,000 ppm. 
     
     
       3. The composition according to claim 1, wherein the at least one tea polyphenol comprises at least one catechin. 
     
     
       4. The composition according to claim 1, wherein the fluoride is fluorosodium. 
     
     
       5. The composition according to claim 1, wherein the at least one tea polyphenol comprises at least one theaflavin. 
     
     
       6. The composition according to claim 1, wherein the fluoride is fluorosodium and the aluminum salt is aluminum lactate or aluminum nitrate. 
     
     
       7. The composition according to claim 1, wherein the at least one polyphenol is contained in a concentration of 100-1,000 ppm, the fluoride is contained in a concentration of 50-500 ppm and the aluminum salt is contained in a concentration of 100-1,000 ppm. 
     
     
       8. The composition according to claim 7, wherein the fluoride is fluorosodium and the aluminum salt is aluminum lactate or aluminum nitrate. 
     
     
       9. The composition according to claim 8, wherein the at least one tea polyphenol comprises epigallocatechin, epicatechin, epigallocatechin gallate and epicatechin gallate. 
     
     
       10. The composition according to claim 9, wherein the at least one tea polyphenol further comprises gallocatechin. 
     
     
       11. A toothpaste comprising the composition according to claim 1, in combination with calcium phosphate, sodium carboxymethyl cellulose, glycerin, lauryl sodium sulfate, aromatic substances, sodium saccharin and water. 
     
     
       12. A mouthwash comprising the composition according to claim 1, in combination with ethanol, sodium saccharin, aromatic substances, a fatty acid ester of sucrose and water. 
     
     
       13. A method for strengthening the acid resistance of teeth by applying to the teeth of a patient in need thereof an effective acid resistance strengthening amount of the composition of claim 1. 
     
     
       14. The method according to claim 13, wherein the at least one polyphenol is contained in a concentration of 100-1,000 ppm, the fluoride is contained in a concentration of 50-500 ppm, the aluminum salt is contained in a concentration of 100-1,000 ppm, the fluoride is fluorosodium, the aluminum salt is aluminum lactate or aluminum nitrate, and the at least one tea polyphenol comprises epigallocatechin, epicatechin, epigallocatechin gallate and epicatechin gallate. 
     
     
       15. The composition according to claim 11, which consists essentially of:   ______________________________________                                    
                   weight %                                               
______________________________________                                    
secondary calcium phosphate                                               
                     45                                                   
sodium carboxymethyl cellulose                                            
                     1.0                                                  
glycerin             20                                                   
lauryl sodium sulfate                                                     
                     1.0                                                  
aromatic substances  1.0                                                  
sodium saccharin     0.2                                                  
tea polyphenol       0.1                                                  
aluminum nitrate     0.01-0.1                                             
sodium fluoride       0.005-0.05,                                         
with the balance being water.                                             
______________________________________                                    
     
     
     
       16. The composition according to claim 12, which consists essentially of   ______________________________________                                    
                  weight %                                                
______________________________________                                    
ethanol             20                                                    
sodium saccharin    0.1                                                   
aromatic substances 1.0                                                   
fatty acid ester of sucrose                                               
                    0.5                                                   
tea polyphenol      0.1                                                   
aluminum lactate    0.001-0.01                                            
sodium fluoride      0.0005-0.005,                                        
with the balance being water.                                             
______________________________________

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