P
US7868047B2ExpiredUtilityPatentIndex 90

Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues

Assignee: WELICHEM BIOTECH INCPriority: Dec 6, 1999Filed: Dec 3, 2007Granted: Jan 11, 2011
Est. expiryDec 6, 2019(expired)· nominal 20-yr term from priority
Inventors:CHEN GENHUIWEBSTER JOHN MLI JIANXIONGHU KAJIZHU JIANGLIU WEI
A61P 37/00A61P 35/00A61P 43/00A61K 47/06C07D 303/16A61P 17/06A61K 47/12A61K 31/336A61K 47/14A61K 31/047C07D 303/14C07D 303/22A61K 47/10A61K 9/0019A61K 9/0014C07D 405/04A61K 31/05
90
PatentIndex Score
17
Cited by
57
References
3
Claims

Abstract

The present invention provides novel methods of treating psoriasis, protein tyrosine kinase-associated disorders, inflammation, epidermal hyperproliferation, diabetes, immune and autoimmune diseases, eczema, and inflammatory bowel disease, inhibiting protein kinase, neutrophil activation, cell proliferation, tumour growth, metastasis, and the development of atheromatous plaque and restonosis, controlling angiogenesis, and preventing inflammatory bowel disease, using hydroxystilbenes and novel stilbene derivatives.

Claims

exact text as granted — not AI-modified
1. A method of treating psoriasis comprising administering to a patient a pharmaceutical composition comprising 3,5-dihydroxy-4-isopropylstilbene. 
     
     
       2. A method of treating eczema comprising administering to a patient a pharmaceutical composition comprising 3,5-dihydroxy-4-isopropylstilbene. 
     
     
       3. A method of treating inflammatory disorders comprising administering to a patient a pharmaceutical composition comprising 3,5-dihydroxy-4-isopropylstilbene.

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