Topic leaderboard
Heterocyclic compounds
Ranked by the PatentIndex Score — a 1–99 percentile within C07D · public-visibility date · generated 2026
top 25 per window · public-visibility date
Rising· last 2 yrs
Inventors whose newest C07D patents became public in the last 2 years — the current frontier
- 199Erik Verner97 patents · 4,755 citations
- 296Hui Li187 patents · 5,096 citations
- 392Louis Grenier39 patents · 1,587 citations
- 488George W. Griesgraber45 patents · 4,480 citations
- 583Stephen Yue62 patents · 3,119 citations
- 679Ravi V. J. Chari76 patents · 3,131 citations
- 775Christopher M. Tegley74 patents · 3,637 citations
- 871Jinglan Zhou102 patents · 5,304 citations
- 967Jason Mccartney72 patents · 4,121 citations
- 1063Ronald Knegtel110 patents · 3,658 citations
- 1158Ish Khanna77 patents · 2,715 citations
- 1254Muthiah Manoharan53 patents · 2,514 citations
- 1350Darren Magda27 patents · 3,273 citations
- 1446Mark Miller103 patents · 5,697 citations
- 1542Brian Bear74 patents · 4,269 citations
- 1638Sara S. Hadida Ruah88 patents · 4,084 citations
- 1733Matthew Hamilton55 patents · 2,484 citations
- 1829Dennis C. Liotta84 patents · 2,315 citations
- 1925Stacey Shepard58 patents · 2,323 citations
- 2021Lee D. Arnold58 patents · 3,300 citations
- 2117Muthusamy Jayaraman42 patents · 1,711 citations
- 2213Kallanthottathil G. Rajeev42 patents · 1,671 citations
- 238Pan Li61 patents · 2,126 citations
- 244Fredrick Van Goor48 patents · 2,931 citations
- 251Wei He69 patents · 1,520 citations
Active· last 5 yrs
Sustained C07D output across the last 5 years
- 199Mark Matteucci16 patents · 5,777 citations
- 296Mark E. Thompson72 patents · 7,200 citations
- 392Jonathan L. Sessler67 patents · 6,992 citations
- 488Dennis W. Solas22 patents · 4,512 citations
- 583Erik Verner97 patents · 4,755 citations
- 679Zhengying Pan42 patents · 3,234 citations
- 775Bryon A. Merrill73 patents · 9,739 citations
- 871Michael J. Rice51 patents · 5,357 citations
- 967Rajinder Singh342 patents · 5,801 citations
- 1063Hui Li187 patents · 5,096 citations
- 1158Ankush Argade99 patents · 3,809 citations
- 1254Somasekhar Bhamidipati137 patents · 3,647 citations
- 1350Jeffrey Clough86 patents · 3,429 citations
- 1446Holger Keim62 patents · 3,215 citations
- 1542Sacha Holland84 patents · 2,331 citations
- 1638Louis Grenier39 patents · 1,587 citations
- 1733George W. Muller167 patents · 9,477 citations
- 1829Stephen R. Forrest34 patents · 5,121 citations
- 1925Roger Shen-Chu Chen59 patents · 4,226 citations
- 2021George W. Griesgraber45 patents · 4,480 citations
- 2117Zhaoyin Wang42 patents · 3,310 citations
- 2213Alfred P. Spada55 patents · 5,652 citations
- 238Stephen Yue62 patents · 3,119 citations
- 244Yves Leblanc37 patents · 3,005 citations
- 251Ravi V. J. Chari76 patents · 3,131 citations
All-time canon
Career PatentIndex Score in C07D
- 199Stephen P. A. Fodor39 patents · 22,227 citations
- 296Lubert Stryer33 patents · 20,303 citations
- 392Michael C. Pirrung39 patents · 19,707 citations
- 488J. Leighton Read28 patents · 17,971 citations
- 583Phillip Dan Cook50 patents · 18,398 citations
- 679Yogesh S. Sanghvi21 patents · 12,008 citations
- 775Mark Matteucci16 patents · 5,777 citations
- 871Mark E. Thompson72 patents · 7,200 citations
- 967Jonathan L. Sessler67 patents · 6,992 citations
- 1063Dennis W. Solas22 patents · 4,512 citations
- 1158John F. Gerster73 patents · 10,385 citations
- 1254Kyle J. Lindstrom83 patents · 11,038 citations
- 1350Philip D. Cook5 patents · 5,233 citations
- 1446Tarak D. Mody47 patents · 4,441 citations
- 1542Erik Verner97 patents · 4,755 citations
- 1638Lee Honigberg51 patents · 3,577 citations
- 1733Zhengying Pan42 patents · 3,234 citations
- 1829Stephen L. Crooks39 patents · 6,745 citations
- 1925William J. Dower9 patents · 3,270 citations
- 2021Bryon A. Merrill73 patents · 9,739 citations
- 2117Motowo Izawa6 patents · 3,826 citations
- 2213Robert D'Amato16 patents · 1,903 citations
- 238Mitsuko Asai16 patents · 3,892 citations
- 244Thomas Gadek56 patents · 5,093 citations
- 251Li-Qiang Sun81 patents · 4,210 citations
Rising· last 2 yrs
The top-scoring C07D patents made public in the last 2 years
- 199US12117439B2✦ AICompositions and methods for using fixed biological samples34 cites · 202484% earned
- 296US12365669B2✦ AITHRβ receptor agonist compound and preparation method and use thereof3 cites · 202559% earned
- 392US12006293B1✦ AIBis diselenide-based schiff bases as deubiquitination signaling pathway modulators7 cites · 202486% earned
- 488US12344585B2Crystalline salts of a plasma kallikrein inhibitor6 cites · 202461% earned
- 583US12226428B2Catecholamine prodrugs for use in the treatment of Parkinson's disease6 cites · 202468% earned
- 679US12297182B2Compositions comprising an urolithin compound4 cites · 202467% earned
- 775US12128033B2Synthetic methods for preparation of 4-(2-chloro-4-methoxy-5-methylphenyl)-n-[(1S)-2-cyclo4 cites · 202467% earned
- 871US12102616B2Psilocin mucate4 cites · 202470% earned
- 967US12404534B1Method for separating amoxicillin and phenylacetic acid from reaction solution in one-step2 cites · 202576% earned
- 1063US12258341B2IRAK degraders and uses thereof5 cites · 202467% earned
- 1158US11964958B1Vaporizable alkaloid compositions and methods of use thereof5 cites · 202469% earned
- 1254US12006305B2Salts of obicetrapib and processes for their manufacture and intermediates thereof5 cites · 202472% earned
- 1350US12187746B2C26-linked rapamycin analogs as mTOR inhibitors5 cites · 202477% earned
- 1446US11919847B1Method for producing high-performance aviation fuel blendstocks from monoterpenes5 cites · 202484% earned
- 1542US12109216B2Methods for treating subjects with Prader-Willi syndrome or Smith-Magenis syndrome3 cites · 202456% earned
- 1638US12180217B2Compounds and methods for treatment of viral infections3 cites · 202457% earned
- 1733US12234236B1GLP-1R agonist and therapeutic method thereof3 cites · 202561% earned
- 1829US12195460B2Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors3 cites · 202463% earned
- 1925US12221442B2Heterocyclic GLP-1 agonists3 cites · 202463% earned
- 2021US12297226B2Compounds and methods for treatment of viral infections3 cites · 202467% earned
- 2117US12209081B2Heterocycle derivatives for treating TRPM3 mediated disorders3 cites · 202467% earned
- 2213US12286427B2Heterocyclic compounds and uses thereof3 cites · 202472% earned
- 238US12151995B2Compounds and compositions for intracellular delivery of therapeutic agents4 cites · 202456% earned
- 244US12202809B2Benzothia(di)azepine compounds and their use as bile acid modulators4 cites · 202467% earned
- 251US12145935B2Inhibitors of (α-v)(β-6) integrin4 cites · 202467% earned
Active· last 5 yrs
The top-scoring C07D patents of the last 5 years
- 199US11124497B1✦ AIInhibitors of cysteine proteases and methods of use thereof57 cites · 202180% earned
- 296US12117439B2✦ AICompositions and methods for using fixed biological samples34 cites · 202484% earned
- 392US11319319B1✦ AICompounds for inhibiting NLRP3 and uses thereof45 cites · 202276% earned
- 488US11185535B2Amorphous kinase inhibitor formulations and methods of use thereof39 cites · 202178% earned
- 583US11242318B2Deuterated tryptamine derivatives and methods of use38 cites · 202174% earned
- 679US10934302B1SHP2 phosphatase inhibitors and methods of use thereof44 cites · 202183% earned
- 775US11395818B2Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-336 cites · 202171% earned
- 871US11174231B1Inhibitors of cysteine proteases and methods of use thereof36 cites · 202184% earned
- 967US11312684B1Pharmaceutically acceptable salts of psilocin and uses thereof31 cites · 202281% earned
- 1063US11246933B1Biodegradable lipids for the delivery of active agents30 cites · 202270% earned
- 1158US11111224B2Benzothia(di)azepine compounds and their use as bile acid modulators30 cites · 202183% earned
- 1254US11014898B1Benzothiazepine compounds and their use as bile acid modulators30 cites · 202186% earned
- 1350US11198697B1Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazi29 cites · 202165% earned
- 1446US11524964B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazi21 cites · 202290% earned
- 1542US11512092B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazi21 cites · 202290% earned
- 1638US10905768B1Heterocyclic degronimers for target protein degradation31 cites · 202181% earned
- 1733USRE48731EDihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment 36 cites · 202182% earned
- 1829US11180465B2Benzothia(di)azepine compounds and their use as bile acid modulators25 cites · 202180% earned
- 1925US11365198B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazi25 cites · 202282% earned
- 2021US11034705B2Fused tricyclic ring derivatives as Src homology-2 phosphate inhibitors29 cites · 202179% earned
- 2117US11535625B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]-pyrazin-8-yl)-N-(2,219 cites · 202275% earned
- 2213US11117889B1IRAK degraders and uses thereof28 cites · 202179% earned
- 238US11225466B2Benzothiadiazepine compounds and their use as bile acid modulators23 cites · 202190% earned
- 244US11180517B2Preparation of psilocybin, different polymorphic forms, intermediates, formulations and th22 cites · 202169% earned
- 251US11618751B1Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives17 cites · 202378% earned
All-time canon
The defining C07D patents of the whole record
- 199US5143854A✦ AILarge scale photolithographic solid phase synthesis of polypeptides and receptor binding s3,709 cites · 199285% earned
- 296US5445934A✦ AIArray of oligonucleotides on a solid substrate3,129 cites · 199584% earned
- 392US5744305A✦ AIArrays of materials attached to a substrate3,038 cites · 199887% earned
- 488US6303238B1OLEDs doped with phosphorescent compounds2,891 cites · 200187% earned
- 583US5602240ABackbone modified oligonucleotide analogs2,348 cites · 199796% earned
- 679US4897355AN[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammoni1,854 cites · 199090% earned
- 775US5489677AOligonucleoside linkages containing adjacent oxygen and nitrogen atoms1,836 cites · 199696% earned
- 871US5800992AMethod of detecting nucleic acids1,804 cites · 199888% earned
- 967US5216141AOligonucleotide analogs containing sulfur linkages1,797 cites · 199396% earned
- 1063US5424186AVery large scale immobilized polymer synthesis1,758 cites · 199593% earned
- 1158US5519134APyrrolidine-containing monomers and oligomers1,700 cites · 199693% earned
- 1254US5608046AConjugated 4'-desmethyl nucleoside analog compounds1,669 cites · 199796% earned
- 1350US5610289ABackbone modified oligonucleotide analogues1,639 cites · 199791% earned
- 1446US5502177APyrimidine derivatives for labeled binding partners1,579 cites · 199689% earned
- 1542US7439354B2Process for preparing amide acetals1,465 cites · 200595% earned
- 1638US5288514ASolid phase and combinatorial synthesis of benzodiazepine compounds on a solid support1,447 cites · 199493% earned
- 1733US5596086AModified internucleoside linkages having one nitrogen and two carbon atoms1,435 cites · 199795% earned
- 1829US5623070AHeteroatomic oligonucleoside linkages1,420 cites · 199791% earned
- 1925US5138045APolyamine conjugated oligonucleotides1,414 cites · 199295% earned
- 2021US5541307ABackbone modified oligonucleotide analogs and solid phase synthesis thereof1,382 cites · 199695% earned
- 2117US6268490B1Bicyclonucleoside and oligonucleotide analogues1,312 cites · 200195% earned
- 2213US5618704ABackbone-modified oligonucleotide analogs and preparation thereof through radical coupling1,294 cites · 199793% earned
- 238US5510270ASynthesis and screening of immobilized oligonucleotide arrays1,288 cites · 199683% earned
- 244US6835469B2Phosphorescent compounds and devices comprising the same1,278 cites · 200395% earned
- 251US5677437AHeteroatomic oligonucleoside linkages1,250 cites · 199795% earned
Rising· last 2 yrs
Assignees whose newest C07D patents became public in the last 2 years — the current frontier
- 199GILEAD SCIENCES INC500 patents · 9,871 citations
- 296UNIV TEXAS295 patents · 7,892 citations
- 392CELGENE CORP279 patents · 10,830 citations
- 488CHILDRENS MEDICAL CENTER37 patents · 2,331 citations
- 583PFIZER2,646 patents · 42,059 citations
- 679IMMUNOGEN INC108 patents · 4,069 citations
- 775UNIV CALIFORNIA641 patents · 11,143 citations
- 871BRISTOL MYERS SQUIBB CO1,900 patents · 28,195 citations
- 967UNIV SOUTHERN CALIFORNIA69 patents · 3,635 citations
- 1063NOVARTIS AG872 patents · 11,196 citations
- 1158VERTEX PHARMA680 patents · 22,144 citations
- 1254LILLY CO ELI2,279 patents · 28,213 citations
- 1350UNIV NORTHEASTERN29 patents · 1,810 citations
- 1446UNIV LELAND STANFORD JUNIOR144 patents · 3,141 citations
- 1542UNIV EMORY162 patents · 3,010 citations
- 1638BAYER AG3,657 patents · 45,618 citations
- 1733INCYTE CORP459 patents · 7,385 citations
- 1829UNIV NORTHWESTERN175 patents · 1,493 citations
- 1925HOFFMANN LA ROCHE2,639 patents · 26,369 citations
- 2021SANOFI SA411 patents · 6,257 citations
- 2117UNIV FLORIDA185 patents · 4,006 citations
- 2213HARVARD COLLEGE176 patents · 3,084 citations
- 238UNIV COLUMBIA124 patents · 2,003 citations
- 244INTRA CELLULAR THERAPIES INC99 patents · 1,913 citations
- 251JANSSEN PHARMACEUTICA NV1,303 patents · 12,583 citations
Active· last 5 yrs
Sustained C07D output across the last 5 years
- 199GILEAD SCIENCES INC500 patents · 9,871 citations
- 296UNIV TEXAS295 patents · 7,892 citations
- 392CELGENE CORP279 patents · 10,830 citations
- 4883M INNOVATIVE PROPERTIES CO260 patents · 16,885 citations
- 583CHILDRENS MEDICAL CENTER37 patents · 2,331 citations
- 679RIGEL PHARMACEUTICALS INC249 patents · 4,488 citations
- 775PFIZER2,646 patents · 42,059 citations
- 871PROCTER & GAMBLE255 patents · 7,833 citations
- 967IMMUNOGEN INC108 patents · 4,069 citations
- 1063UNIV PRINCETON68 patents · 5,496 citations
- 1158DU PONT1,447 patents · 23,037 citations
- 1254UNIV CALIFORNIA641 patents · 11,143 citations
- 1350BRISTOL MYERS SQUIBB CO1,900 patents · 28,195 citations
- 1446UNIV SOUTHERN CALIFORNIA69 patents · 3,635 citations
- 1542NOVARTIS AG872 patents · 11,196 citations
- 1638VERTEX PHARMA680 patents · 22,144 citations
- 1733LIGAND PHARM INC87 patents · 2,965 citations
- 1829LILLY CO ELI2,279 patents · 28,213 citations
- 1925GENTEX CORP30 patents · 2,380 citations
- 2021UNIV NORTHEASTERN29 patents · 1,810 citations
- 2117OREAL297 patents · 5,208 citations
- 2213UNIV LELAND STANFORD JUNIOR144 patents · 3,141 citations
- 238HEALTH RESEARCH INC41 patents · 2,806 citations
- 244UNIV EMORY162 patents · 3,010 citations
- 251BAYER AG3,657 patents · 45,618 citations
All-time canon
All-time PatentIndex Score in C07D
- 199AFFYMAX TECH NV21 patents · 14,845 citations
- 296ISIS PHARMACEUTICALS INC80 patents · 20,601 citations
- 392AFFYMETRIX INC32 patents · 8,526 citations
- 488GILEAD SCIENCES INC500 patents · 9,871 citations
- 583PHARMACYCLICS INC53 patents · 3,596 citations
- 679UNIV TEXAS295 patents · 7,892 citations
- 775CELGENE CORP279 patents · 10,830 citations
- 871MINNESOTA MINING & MFG195 patents · 13,168 citations
- 9673M INNOVATIVE PROPERTIES CO260 patents · 16,885 citations
- 1063TAKEDA CHEMICAL INDUSTRIES LTD791 patents · 25,262 citations
- 1158CHILDRENS MEDICAL CENTER37 patents · 2,331 citations
- 1254SUGEN INC114 patents · 6,263 citations
- 1350RIGEL PHARMACEUTICALS INC249 patents · 4,488 citations
- 1446MERCK & CO INC2,674 patents · 58,940 citations
- 1542SYNTEX INC385 patents · 11,054 citations
- 1638CIBA GEIGY CORP2,500 patents · 38,859 citations
- 1733WARNER LAMBERT CO1,135 patents · 28,321 citations
- 1829PFIZER2,646 patents · 42,059 citations
- 1925PROCTER & GAMBLE255 patents · 7,833 citations
- 2021IMMUNOGEN INC108 patents · 4,069 citations
- 2117HONIGBERG LEE26 patents · 1,990 citations
- 2213UNIV PRINCETON68 patents · 5,496 citations
- 238MERCK FROSST CANADA INC186 patents · 8,530 citations
- 244DU PONT1,447 patents · 23,037 citations
- 251UNIV CALIFORNIA641 patents · 11,143 citations
90–99 field-defining50–89 strong<50 emergingearned by citationsfrom family breadth