Topic leaderboard
Peptides & proteins
Ranked by the PatentIndex Score — a 1–99 percentile within C07K · public-visibility date · generated 2026
top 25 per window · public-visibility date
Rising· last 2 yrs
Inventors whose newest C07K patents became public in the last 2 years — the current frontier
- 199Leonard G. Presta212 patents · 40,855 citations
- 296Nils Lonberg66 patents · 38,234 citations
- 392Daniel J. Capon49 patents · 17,410 citations
- 488Alan J. Korman85 patents · 7,903 citations
- 583Carl H. June106 patents · 14,588 citations
- 679Mark J. Selby81 patents · 6,550 citations
- 775Henry B. Lowman94 patents · 8,651 citations
- 871Gary J. Nabel89 patents · 9,355 citations
- 967Elizabeth Sally Ward15 patents · 5,246 citations
- 1063John Robert Adair18 patents · 6,036 citations
- 1158John Spencer Emtage18 patents · 7,260 citations
- 1254Guangping Gao69 patents · 4,594 citations
- 1350H. Michael Shepard38 patents · 3,905 citations
- 1446Jeffrey A. Ledbetter82 patents · 10,272 citations
- 1542Bradley R. Snedecor17 patents · 5,412 citations
- 1638Diljeet Singh Athwal21 patents · 4,606 citations
- 1733Dennis R. Burton55 patents · 8,607 citations
- 1829George D. Yancopoulos164 patents · 6,447 citations
- 1925Antonin De Fougerolles70 patents · 4,353 citations
- 2021Jason P. Schrum30 patents · 2,715 citations
- 2117Michael C. Jensen61 patents · 3,951 citations
- 2213Radoje Drmanac46 patents · 1,968 citations
- 238David M. Goldenberg329 patents · 10,419 citations
- 244Andrew J. Murphy331 patents · 5,348 citations
- 251David R. Liu96 patents · 5,394 citations
Active· last 5 yrs
Sustained C07K output across the last 5 years
- 199Leonard G. Presta212 patents · 40,855 citations
- 296Nils Lonberg66 patents · 38,234 citations
- 392Paul Carter51 patents · 18,811 citations
- 488Aya Jakobovits186 patents · 18,318 citations
- 583James D. Marks75 patents · 10,671 citations
- 679John Mccafferty28 patents · 9,125 citations
- 775Daniel J. Capon49 patents · 17,410 citations
- 871Hendricus Renerus Jacobus Mattheus Hoogenboom35 patents · 10,291 citations
- 967William J. Dower68 patents · 17,493 citations
- 1063Alan J. Korman85 patents · 7,903 citations
- 1158Carl H. June106 patents · 14,588 citations
- 1254Mark J. Selby81 patents · 6,550 citations
- 1350Mohan Srinivasan67 patents · 6,452 citations
- 1446Changyu Wang27 patents · 5,869 citations
- 1542Henry B. Lowman94 patents · 8,651 citations
- 1638Craig B. Thompson25 patents · 9,989 citations
- 1733Gary J. Nabel89 patents · 9,355 citations
- 1829Paul Rennert33 patents · 8,902 citations
- 1925Elizabeth Sally Ward15 patents · 5,246 citations
- 2021Carlos F. Barbas, Iii51 patents · 6,570 citations
- 2117Willem P. Stemmer24 patents · 6,059 citations
- 2213James A. Wells56 patents · 8,395 citations
- 238James M. Wilson120 patents · 8,704 citations
- 244John Robert Adair18 patents · 6,036 citations
- 251John Spencer Emtage18 patents · 7,260 citations
All-time canon
Career PatentIndex Score in C07K
- 199Cary L. Queen18 patents · 28,819 citations
- 296Harold E. Selick7 patents · 25,683 citations
- 392Stephen P. A. Fodor68 patents · 32,091 citations
- 488Lubert Stryer36 patents · 19,259 citations
- 583Michael C. Pirrung33 patents · 18,082 citations
- 679J. Leighton Read29 patents · 18,080 citations
- 775Robert Charles Ladner84 patents · 27,219 citations
- 871Leonard G. Presta212 patents · 40,855 citations
- 967Nils Lonberg66 patents · 38,234 citations
- 1063Robert M. Kay21 patents · 34,709 citations
- 1158Gregory Paul Winter70 patents · 36,410 citations
- 1254Paul Carter51 patents · 18,811 citations
- 1350Arthur C. Ley17 patents · 15,048 citations
- 1446Rachel Kent14 patents · 14,880 citations
- 1542Sonia Guterman12 patents · 14,386 citations
- 1638William Markland24 patents · 14,390 citations
- 1733Aya Jakobovits186 patents · 18,318 citations
- 1829Raju Kucherlapati16 patents · 13,120 citations
- 1925Andrew David Griffiths33 patents · 13,658 citations
- 2021James D. Marks75 patents · 10,671 citations
- 2117John Mccafferty28 patents · 9,125 citations
- 2213Casey C. Case18 patents · 7,128 citations
- 238Daniel J. Capon49 patents · 17,410 citations
- 244Hendricus Renerus Jacobus Mattheus Hoogenboom35 patents · 10,291 citations
- 251Stephen P. Eisenberg29 patents · 6,956 citations
Rising· last 2 yrs
The top-scoring C07K patents made public in the last 2 years
- 199US12018274B2✦ AICompositions and methods for regulating production of a fusion protein and ribonucleic aci79 cites · 202493% earned
- 296US12097263B2✦ AIMuscle targeting complexes and uses thereof for treating myotonic dystrophy18 cites · 202481% earned
- 392US11969475B2✦ AIMuscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dyst25 cites · 202475% earned
- 488US12005124B2Muscle targeting complexes and uses thereof for treating dystrophinopathies23 cites · 202473% earned
- 583US12018087B2Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an o23 cites · 202477% earned
- 679US12012460B2Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an o22 cites · 202471% earned
- 775US12144867B2Muscle targeting complexes and uses thereof for treating dystrophinopathies14 cites · 202475% earned
- 871US11999947B2Adenosine nucleobase editors and uses thereof18 cites · 202477% earned
- 967US12128109B2Muscle targeting complexes and formulations for treating dystrophinopathies17 cites · 202484% earned
- 1063US12169198B2Systems and methods for sample analysis15 cites · 202483% earned
- 1158US12329825B1Muscle targeting complexes comprising an anti-transferrin receptor antibody linked to an o4 cites · 202570% earned
- 1254US12030915B2Mutated glycoprotein of vesicular stomatitis virus10 cites · 202468% earned
- 1350US12121587B1Dimeric antibodies10 cites · 202481% earned
- 1446US12116410B1Methods of manufacturing dimeric antibodies10 cites · 202481% earned
- 1542US11939384B1Antibody variable domains targeting the NKG2D receptor9 cites · 202472% earned
- 1638US12122840B2Method of modifying isoelectric point of antibody via amino acid substitution in CDR5 cites · 202463% earned
- 1733US11965000B2Respiratory syncytial virus (RSV) vaccine7 cites · 202464% earned
- 1829US11980643B2Method and system to modify an individual's gut-brain axis to provide neurocognitive p7 cites · 202486% earned
- 1925US11987638B1Prevention of disulfide bond reduction during recombinant production of polypeptides4 cites · 202452% earned
- 2021US12084696B2Compositions and methods for using engineered deubiquitinases for probing ubiquitin-depend6 cites · 202463% earned
- 2117US12187797B2SIRP α, SIRP β 1, and SIRP γ antibodies and uses thereof4 cites · 202470% earned
- 2213US12173081B2CD19/CD38 multispecific antibodies4 cites · 202475% earned
- 238US12351653B1Pharmaceutical compositions comprising novel cyclic peptides2 cites · 202567% earned
- 244US12370264B1Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide an2 cites · 202576% earned
- 251US12116389B2Dual cytokine fusion proteins comprising IL-105 cites · 202454% earned
Active· last 5 yrs
The top-scoring C07K patents of the last 5 years
- 199US11951186B2✦ AIIndicator compounds, devices comprising indicator compounds, and methods of making and usi131 cites · 202190% earned
- 296US12018274B2✦ AICompositions and methods for regulating production of a fusion protein and ribonucleic aci79 cites · 202493% earned
- 392US11447770B1✦ AIMethods and compositions for prime editing nucleotide sequences81 cites · 202278% earned
- 488US11873505B2Compositions and methods for regulating production of a precursor protein81 cites · 202289% earned
- 583US11111309B2Method of reducing expression of DUX4 in a muscle cell by administering an anti-transferri65 cites · 202177% earned
- 679US11467153B2Methods for processing nucleic acid molecules62 cites · 202188% earned
- 775US11369689B2Muscle targeting complexes and uses thereof for treating dystrophinopathies48 cites · 202277% earned
- 871US11638761B2Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dyst47 cites · 202383% earned
- 967US11168141B2Muscle targeting complexes and uses thereof for treating dystrophinopathies53 cites · 202185% earned
- 1063US11648318B2Anti-transferrin receptor (TFR) antibody and uses thereof37 cites · 202384% earned
- 1158US11633498B2Muscle targeting complexes and uses thereof for treating myotonic dystrophy37 cites · 202391% earned
- 1254US12097263B2Muscle targeting complexes and uses thereof for treating myotonic dystrophy18 cites · 202481% earned
- 1350US11931421B2Muscle targeting complexes and formulations for treating myotonic dystrophy26 cites · 202379% earned
- 1446US11969475B2Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dyst25 cites · 202475% earned
- 1542US11771776B2Muscle targeting complexes and uses thereof for treating dystrophinopathies32 cites · 202380% earned
- 1638US11406703B2Human cytomegalovirus vaccine39 cites · 202291% earned
- 1733US12018087B2Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an o23 cites · 202477% earned
- 1829US11203612B2Methods of generating nanoarrays and microarrays45 cites · 202181% earned
- 1925US11045546B1Methods of treating coronavirus infection39 cites · 202191% earned
- 2021US10973909B1Coronavirus vaccine39 cites · 202191% earned
- 2117US11203767B2Circular RNA for translation in eukaryotic cells30 cites · 202175% earned
- 2213US11702651B2Adenosine nucleobase editors and uses thereof29 cites · 202179% earned
- 238US12128109B2Muscle targeting complexes and formulations for treating dystrophinopathies17 cites · 202484% earned
- 244US11117945B2T-cell modulatory multimeric polypeptides and methods of use thereof28 cites · 202169% earned
- 251US11311627B1Nucleic acid-polypeptide compositions and methods of inducing exon skipping28 cites · 202275% earned
All-time canon
The defining C07K patents of the whole record
- 199US4816567A✦ AIRecombinant immunoglobin preparations13,882 cites · 198993% earned
- 296US4683202A✦ AIProcess for amplifying nucleic acid sequences13,211 cites · 198796% earned
- 392US5585089A✦ AIHumanized immunoglobulins7,465 cites · 199690% earned
- 488US5223409ADirected evolution of novel binding proteins6,875 cites · 199389% earned
- 583US4946778ASingle polypeptide chain binding molecules6,695 cites · 199096% earned
- 679US5225539ARecombinant altered antibodies and methods of making altered antibodies5,993 cites · 199396% earned
- 775US5530101AHumanized immunoglobulins5,773 cites · 199690% earned
- 871US5545806ARansgenic non-human animals for producing heterologous antibodies5,538 cites · 199696% earned
- 967US5693762AHumanized immunoglobulins5,271 cites · 199790% earned
- 1063US5569825ATransgenic non-human animals capable of producing heterologous antibodies of various isoty4,704 cites · 199696% earned
- 1158US5633425ATransgenic non-human animals capable of producing heterologous antibodies4,435 cites · 199796% earned
- 1254US5625126ATransgenic non-human animals for producing heterologous antibodies4,338 cites · 199796% earned
- 1350US4179337ANon-immunogenic polypeptides4,333 cites · 197996% earned
- 1446US5545807AProduction of antibodies from transgenic animals4,332 cites · 199696% earned
- 1542US5661016ATransgenic non-human animals capable of producing heterologous antibodies of various isoty4,236 cites · 199796% earned
- 1638US5821337AImmunoglobulin variants4,043 cites · 199891% earned
- 1733US5565332AProduction of chimeric antibodies - a combinatorial approach3,895 cites · 199696% earned
- 1829US5624821AAntibodies with altered effector functions3,801 cites · 199794% earned
- 1925US5143854ALarge scale photolithographic solid phase synthesis of polypeptides and receptor binding s3,709 cites · 199285% earned
- 2021US6180370B1Humanized immunoglobulins and methods of making the same3,646 cites · 200189% earned
- 2117US5034506AUncharged morpholino-based polymers having achiral intersubunit linkages3,553 cites · 199196% earned
- 2213US4676980ATarget specific cross-linked heteroantibodies3,427 cites · 198796% earned
- 238US6737056B1Polypeptide variants with altered effector function3,376 cites · 200487% earned
- 244US5648260ADNA encoding antibodies with altered effector functions3,371 cites · 199794% earned
- 251US5693761APolynucleotides encoding improved humanized immunoglobulins3,290 cites · 199789% earned
Rising· last 2 yrs
Assignees whose newest C07K patents became public in the last 2 years — the current frontier
- 199GENENTECH INC2,131 patents · 124,674 citations
- 296SCRIPPS RESEARCH INST429 patents · 19,507 citations
- 392UNIV PENNSYLVANIA657 patents · 17,294 citations
- 488UNIV TEXAS773 patents · 22,765 citations
- 583UNIV CALIFORNIA2,089 patents · 48,038 citations
- 679US HEALTH1,400 patents · 30,838 citations
- 775REGENERON PHARMA1,030 patents · 15,313 citations
- 871AMGEN INC761 patents · 17,888 citations
- 967IMMUNOMEDICS INC269 patents · 10,392 citations
- 1063MASSACHUSETTS INST TECHNOLOGY370 patents · 10,689 citations
- 1158UNIV LELAND STANFORD JUNIOR605 patents · 14,970 citations
- 1254BRISTOL MYERS SQUIBB CO713 patents · 18,424 citations
- 1350HARVARD COLLEGE501 patents · 17,204 citations
- 1446UNIV ARIZONA120 patents · 8,236 citations
- 1542HOPE CITY200 patents · 5,288 citations
- 1638IMMUNOGEN INC144 patents · 3,815 citations
- 1733MILLENNIUM PHARM INC390 patents · 7,486 citations
- 1829CALIFORNIA INST OF TECHN212 patents · 6,254 citations
- 1925MONSANTO TECHNOLOGY LLC363 patents · 7,677 citations
- 2021UNIV WASHINGTON479 patents · 12,816 citations
- 2117HOFFMANN LA ROCHE634 patents · 11,911 citations
- 2213UNIV NEW YORK290 patents · 5,494 citations
- 238XENCOR INC169 patents · 3,860 citations
- 244UNIV JOHNS HOPKINS424 patents · 8,935 citations
- 251LILLY CO ELI628 patents · 16,915 citations
Active· last 5 yrs
Sustained C07K output across the last 5 years
- 199GENENTECH INC2,131 patents · 124,674 citations
- 296SCRIPPS RESEARCH INST429 patents · 19,507 citations
- 392UNIV PENNSYLVANIA657 patents · 17,294 citations
- 488UNIV TEXAS773 patents · 22,765 citations
- 583UNIV CALIFORNIA2,089 patents · 48,038 citations
- 679US HEALTH1,400 patents · 30,838 citations
- 775REGENERON PHARMA1,030 patents · 15,313 citations
- 871AMGEN INC761 patents · 17,888 citations
- 967IMMUNOMEDICS INC269 patents · 10,392 citations
- 1063MASSACHUSETTS INST TECHNOLOGY370 patents · 10,689 citations
- 1158UNIV LELAND STANFORD JUNIOR605 patents · 14,970 citations
- 1254BRISTOL MYERS SQUIBB CO713 patents · 18,424 citations
- 1350HARVARD COLLEGE501 patents · 17,204 citations
- 1446UNIV ARIZONA120 patents · 8,236 citations
- 1542HOPE CITY200 patents · 5,288 citations
- 1638ABBOTT LAB354 patents · 8,950 citations
- 1733UNIV BRUXELLES16 patents · 1,712 citations
- 1829IMMUNOGEN INC144 patents · 3,815 citations
- 1925AJINOMOTO KK348 patents · 7,660 citations
- 2021SALK INST FOR BIOLOGICAL STUDI340 patents · 11,680 citations
- 2117MILLENNIUM PHARM INC390 patents · 7,486 citations
- 2213CALIFORNIA INST OF TECHN212 patents · 6,254 citations
- 238HEALTH RESEARCH INC85 patents · 4,876 citations
- 244MONSANTO TECHNOLOGY LLC363 patents · 7,677 citations
- 251UNIV WASHINGTON479 patents · 12,816 citations
All-time canon
All-time PatentIndex Score in C07K
- 199PROTEIN DESIGN LABS INC26 patents · 31,274 citations
- 296GENENTECH INC2,131 patents · 124,674 citations
- 392AFFYMAX TECH NV67 patents · 36,702 citations
- 488GENPHARM INT20 patents · 35,794 citations
- 583MEDICAL RES COUNCIL104 patents · 24,279 citations
- 679PROTEIN ENG CORP5 patents · 13,691 citations
- 775ABGENIX INC29 patents · 17,902 citations
- 871SANGAMO BIOSCIENCES INC108 patents · 11,347 citations
- 967AFFYMETRIX INC79 patents · 17,625 citations
- 1063SCRIPPS RESEARCH INST429 patents · 19,507 citations
- 1158MEDAREX INC63 patents · 9,296 citations
- 1254MAXYGEN INC81 patents · 18,120 citations
- 1350UNIV PENNSYLVANIA657 patents · 17,294 citations
- 1446ANTI GENE DEV GROUP5 patents · 8,786 citations
- 1542GENETICS INST193 patents · 17,394 citations
- 1638XOMA CORP88 patents · 9,780 citations
- 1733UNIV TEXAS773 patents · 22,765 citations
- 1829CETUS CORP105 patents · 23,251 citations
- 1925COLLAGEN CORP33 patents · 9,459 citations
- 2021SARNOFF DAVID RES CENTER5 patents · 3,293 citations
- 2117NANOGEN INC46 patents · 7,716 citations
- 2213ISIS PHARMACEUTICALS INC114 patents · 12,213 citations
- 238UNIV CALIFORNIA2,089 patents · 48,038 citations
- 244RHONE POULENC AGROCHIMIE18 patents · 4,665 citations
- 251IDEC PHARMA CORP32 patents · 6,730 citations
90–99 field-defining50–89 strong<50 emergingearned by citationsfrom family breadth