Topic leaderboard
Sugars & nucleic-acid derivatives
Ranked by the PatentIndex Score — a 1–99 percentile within C07H · public-visibility date · generated 2026
top 25 per window · public-visibility date
Rising· last 2 yrs
Inventors whose newest C07H patents became public in the last 2 years — the current frontier
- 199Xiaohai Liu54 patents · 4,207 citations
- 296Eric E. Swayze120 patents · 8,412 citations
- 392Punit P. Seth76 patents · 6,885 citations
- 488Leonid Beigelman132 patents · 7,024 citations
- 583Jingyue Ju67 patents · 2,825 citations
- 679Zengmin Li46 patents · 1,783 citations
- 775Radoje Drmanac26 patents · 1,423 citations
- 871Sergei Gryaznov60 patents · 4,863 citations
- 967Thazha P. Prakash72 patents · 5,124 citations
- 1063Jean-Pierre Sommadossi61 patents · 3,851 citations
- 1158Dennis C. Liotta46 patents · 2,624 citations
- 1254Charles Allerson20 patents · 1,894 citations
- 1350Michael Joseph Sofia40 patents · 2,057 citations
- 1446Peiyuan Wang30 patents · 1,574 citations
- 1542Jinfa Du32 patents · 1,672 citations
- 1638Xiaolin Wu30 patents · 981 citations
- 1733Brian K. Hauser10 patents · 681 citations
- 1829Snezana Drmanac12 patents · 627 citations
- 1925George Yeung9 patents · 618 citations
- 2021Matthew J. Callow9 patents · 618 citations
- 2117Jason P. Schrum10 patents · 629 citations
- 2213Norman C. Nelson14 patents · 1,202 citations
- 238Kenechi Ejebe9 patents · 516 citations
- 244Dhanapalan Nagarathnam17 patents · 1,061 citations
- 251Alexander A. Gall27 patents · 1,271 citations
Active· last 5 yrs
Sustained C07H output across the last 5 years
- 199Mark Matteucci47 patents · 26,125 citations
- 296Muthiah Manoharan184 patents · 18,489 citations
- 392Marvin H. Caruthers47 patents · 14,021 citations
- 488Arthur M. Krieg36 patents · 6,084 citations
- 583Peter Nielsen29 patents · 7,480 citations
- 679Xiaohai Liu54 patents · 4,207 citations
- 775Stanley T. Crooke16 patents · 2,830 citations
- 871Eric E. Swayze120 patents · 8,412 citations
- 967Punit P. Seth76 patents · 6,885 citations
- 1063Leonid Beigelman132 patents · 7,024 citations
- 1158Mark A. Gallop16 patents · 2,514 citations
- 1254Jingyue Ju67 patents · 2,825 citations
- 1350Zengmin Li46 patents · 1,783 citations
- 1446Radoje Drmanac26 patents · 1,423 citations
- 1542Sergei Gryaznov60 patents · 4,863 citations
- 1638John Milton28 patents · 3,380 citations
- 1733Takeshi Imanishi15 patents · 4,302 citations
- 1829Linda G. Lee55 patents · 4,731 citations
- 1925Chad A. Mirkin46 patents · 4,611 citations
- 2021Thazha P. Prakash72 patents · 5,124 citations
- 2117Kallanthottathil G. Rajeev71 patents · 2,531 citations
- 2213Martin Maier28 patents · 1,635 citations
- 238Drew Weissman11 patents · 1,407 citations
- 244Katalin Kariko12 patents · 1,407 citations
- 251Steven Albert Benner33 patents · 5,034 citations
All-time canon
Career PatentIndex Score in C07H
- 199Stephen P. A. Fodor78 patents · 37,522 citations
- 296Lubert Stryer35 patents · 19,998 citations
- 392Michael C. Pirrung31 patents · 18,129 citations
- 488J. Leighton Read29 patents · 18,080 citations
- 583Phillip Dan Cook161 patents · 41,605 citations
- 679Mark Matteucci47 patents · 26,125 citations
- 775Dwight D. Weller26 patents · 14,322 citations
- 871James E. Summerton13 patents · 13,991 citations
- 967Yogesh S. Sanghvi35 patents · 15,059 citations
- 1063Muthiah Manoharan184 patents · 18,489 citations
- 1158Marvin H. Caruthers47 patents · 14,021 citations
- 1254Robert J. Jones24 patents · 10,377 citations
- 1350William J. Dower26 patents · 11,453 citations
- 1446Sudhir Agrawal80 patents · 10,872 citations
- 1542Kuei-Ying Lin27 patents · 7,101 citations
- 1638Jesper Wengel19 patents · 7,492 citations
- 1733Arthur M. Krieg36 patents · 6,084 citations
- 1829Dennis W. Solas18 patents · 8,429 citations
- 1925Michael S. Urdea37 patents · 14,438 citations
- 2021Thomas Horn33 patents · 12,503 citations
- 2117Kanda Ramasamy15 patents · 6,326 citations
- 2213Philip D. Cook7 patents · 6,967 citations
- 238Jonathan L. Sessler44 patents · 5,896 citations
- 244Brian Froehler23 patents · 8,544 citations
- 251Robert L. Letsinger50 patents · 8,394 citations
Rising· last 2 yrs
The top-scoring C07H patents made public in the last 2 years
- 199US12226428B2✦ AICatecholamine prodrugs for use in the treatment of Parkinson's disease6 cites · 202468% earned
- 296US12297226B2✦ AICompounds and methods for treatment of viral infections3 cites · 202467% earned
- 392US12215122B2✦ AINucleotide analogues3 cites · 202457% earned
- 488US12188089B2Cleavable disulfide linkers and uses thereof2 cites · 202461% earned
- 583US12006340B2Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus2 cites · 202453% earned
- 679US11952396B1Crystalline solids of nicotinic acid mononucleotide and esters thereof and methods of maki2 cites · 202467% earned
- 775US12018306B2Method for chemically synthesizing Helicobacter pylori core lipopolysaccharide oligosaccha2 cites · 202476% earned
- 871US12357708B2Modified nucleosides, nucleotides, and nucleic acids, and uses thereof1 cites · 202535% earned
- 967US12522819B2Systems and methods for determining nucleic acids1 cites · 202535% earned
- 1063US12461106B2Ultra bright dimeric or polymeric dyes with spacing linker groups1 cites · 202440% earned
- 1158US12128106B2ASGPR-binding compounds for the degradation of extracellular proteins1 cites · 202440% earned
- 1254US12168023B2Inhibitors of adenosine 5′-nucleotidase1 cites · 202450% earned
- 1350US12134610B2Somatostatin subtype-2 receptor (SST2R) targeted therapeutics and uses thereof1 cites · 202456% earned
- 1446US12084473B2β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides f1 cites · 202435% earned
- 1542US12097231B2Steviol glycoside compositions with reduced surface tension1 cites · 202436% earned
- 1638US12180246B2Utility of nematode small molecules1 cites · 202438% earned
- 1733US12226429B2Highly active compounds against COVID-191 cites · 202442% earned
- 1829US12415835B2Peptide-compound cyclization method1 cites · 202446% earned
- 1925US12428442B2Compounds, compositions and methods for synthesis1 cites · 202450% earned
- 2021US12091663B2Modified ribonucleic acids and uses thereof1 cites · 202450% earned
- 2117US12331057B2Modulators of alpha-1 antitrypsin1 cites · 202456% earned
- 2213US12351599B2Antiviral application of nucleoside analog or combination formulation containing nucleosid1 cites · 202456% earned
- 238US12268702B2Antitumor pharmaceutical composition comprising azvudine and chemotherapeutic agent1 cites · 202467% earned
- 244US11857956B1Solid acid catalyst for preparing D-galactose and preparation method thereof1 cites · 202467% earned
- 251US12121529B2Nucleoside phosphoramidate prodrugs0 cites · 20240% earned
Active· last 5 yrs
The top-scoring C07H patents of the last 5 years
- 199US11141378B2✦ AILipid formulations for nucleic acid delivery42 cites · 202175% earned
- 296US11485960B2✦ AIRNA polymerase variants for co-transcriptional capping40 cites · 202184% earned
- 392US11541071B1✦ AINucleoside derivatives and methods of use thereof23 cites · 202382% earned
- 488US11434374B2Water soluble fluorescent or colored dyes and methods for their use27 cites · 202179% earned
- 583US11174281B1Modified nucleotides and uses thereof24 cites · 202185% earned
- 679US11266666B2Methods for treating Filoviridae virus infections24 cites · 202175% earned
- 775US11999999B2Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA se19 cites · 202275% earned
- 871US11613553B2Methods of preparing 1′-cyano nucleosides19 cites · 202181% earned
- 967US11814406B2Compounds and methods for treatment of viral infections11 cites · 202378% earned
- 1063US11377456B2Crystalline form of Remdesivir16 cites · 202289% earned
- 1158US11492353B2Methods and compounds for treating Paramyxoviridae virus infections19 cites · 202175% earned
- 1254US11597742B2Crystalline forms of (S)-2-ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f] [1,19 cites · 202181% earned
- 1350US11028122B1Antisense nucleic acids14 cites · 202166% earned
- 1446US11958877B2Nucleotide analogues8 cites · 202368% earned
- 1542US11819551B2ASGPR-binding compounds for the degradation of extracellular proteins10 cites · 202370% earned
- 1638US11562103B2Nucleic acid based data storage10 cites · 202273% earned
- 1733US11707476B2Catecholamine prodrugs for use in the treatment of parkinson's disease12 cites · 202274% earned
- 1829US11959075B2Systems and methods for determining nucleic acids7 cites · 202362% earned
- 1925US11638715B2Orally-bioavailable nucleoside analogs9 cites · 202381% earned
- 2021US11001603B2Modulators of 5′-nucleotidase, ecto and the use thereof13 cites · 202175% earned
- 2117US11891457B2Peptide-compound cyclization method12 cites · 202176% earned
- 2213US12006438B2Polymeric dyes with linker groups comprising deoxyribose13 cites · 202279% earned
- 238US11851456B2Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-9 cites · 202277% earned
- 244US11224599B2Therapeutic agents and methods9 cites · 202181% earned
- 251US11512065B2GPR119 agonists7 cites · 202279% earned
All-time canon
The defining C07H patents of the whole record
- 199US5143854A✦ AILarge scale photolithographic solid phase synthesis of polypeptides and receptor binding s3,709 cites · 199285% earned
- 296US5034506A✦ AIUncharged morpholino-based polymers having achiral intersubunit linkages3,553 cites · 199196% earned
- 392US5445934A✦ AIArray of oligonucleotides on a solid substrate3,129 cites · 199584% earned
- 488US5744305AArrays of materials attached to a substrate3,038 cites · 199887% earned
- 583US4458066AProcess for preparing polynucleotides2,902 cites · 198496% earned
- 679US5602240ABackbone modified oligonucleotide analogs2,348 cites · 199796% earned
- 775US4469863ANonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use th2,296 cites · 198496% earned
- 871US5210015AHomogeneous assay system using the nuclease activity of a nucleic acid polymerase2,135 cites · 199389% earned
- 967US5539082APeptide nucleic acids2,083 cites · 199693% earned
- 1063US5235033AAlpha-morpholino ribonucleoside derivatives and polymers thereof2,054 cites · 199396% earned
- 1158US5185444AUncharged morpolino-based polymers having phosphorous containing chiral intersubunit linka2,014 cites · 199396% earned
- 1254US5432272AMethod for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heter1,970 cites · 199593% earned
- 1350US5474796AMethod and apparatus for conducting an array of chemical reactions on a support surface1,844 cites · 199592% earned
- 1446US5489677AOligonucleoside linkages containing adjacent oxygen and nitrogen atoms1,836 cites · 199696% earned
- 1542US5800992AMethod of detecting nucleic acids1,804 cites · 199888% earned
- 1638US7057026B2Labelled nucleotides1,804 cites · 200390% earned
- 1733US5216141AOligonucleotide analogs containing sulfur linkages1,797 cites · 199396% earned
- 1829US5023243AOligonucleotide therapeutic agent and method of making same1,792 cites · 199196% earned
- 1925US5166315ASequence-specific binding polymers for duplex nucleic acids1,783 cites · 199296% earned
- 2021US5424186AVery large scale immobilized polymer synthesis1,758 cites · 199593% earned
- 2117US5484908AOligonucleotides containing 5-propynyl pyrimidines1,715 cites · 199696% earned
- 2213US5459255AN-2 substituted purines1,696 cites · 199590% earned
- 238US5714331APeptide nucleic acids having enhanced binding affinity, sequence specificity and solubilit1,692 cites · 199893% earned
- 244US5270163AMethods for identifying nucleic acid ligands1,688 cites · 199396% earned
- 251US5608046AConjugated 4'-desmethyl nucleoside analog compounds1,669 cites · 199796% earned
Rising· last 2 yrs
Assignees whose newest C07H patents became public in the last 2 years — the current frontier
- 199GILEAD SCIENCES INC140 patents · 24,694 citations
- 296UNIV TEXAS102 patents · 6,346 citations
- 392UNIV COLUMBIA71 patents · 3,463 citations
- 488CALIFORNIA INST OF TECHN59 patents · 5,567 citations
- 583GEN PROBE INC46 patents · 4,182 citations
- 679ILLUMINA CAMBRIDGE LTD59 patents · 2,112 citations
- 775SCRIPPS RESEARCH INST86 patents · 4,588 citations
- 871UNIV CALIFORNIA201 patents · 5,915 citations
- 967UNIV EMORY67 patents · 2,993 citations
- 1063HARVARD COLLEGE84 patents · 2,374 citations
- 1158ALNYLAM PHARMACEUTICALS INC71 patents · 1,658 citations
- 1254REGENERON PHARMA36 patents · 1,205 citations
- 1350AGILENT TECHNOLOGIES INC64 patents · 3,942 citations
- 1446SIRNA THERAPEUTICS INC49 patents · 1,275 citations
- 1542GERON CORP31 patents · 527 citations
- 1638MODERNATX INC23 patents · 394 citations
- 1733UNIV KANSAS20 patents · 848 citations
- 1829COMPLETE GENOMICS INC12 patents · 162 citations
- 1925CARGILL INC25 patents · 486 citations
- 2021NOVARTIS AG40 patents · 641 citations
- 2117MEDIVIR AB26 patents · 481 citations
- 2213PACIFIC BIOSCIENCES CALIFORNIA INC40 patents · 449 citations
- 238WAVE LIFE SCIENCES LTD25 patents · 402 citations
- 244ROQUETTE FRERES39 patents · 549 citations
- 251ATEA PHARMACEUTICALS INC23 patents · 226 citations
Active· last 5 yrs
Sustained C07H output across the last 5 years
- 199GILEAD SCIENCES INC140 patents · 24,694 citations
- 296UNIV IOWA RES FOUND53 patents · 8,094 citations
- 392US HEALTH101 patents · 8,145 citations
- 488UNIV TEXAS102 patents · 6,346 citations
- 583CENTRE NAT RECH SCIENT38 patents · 5,364 citations
- 679MAX PLANCK GESELLSCHAFT25 patents · 2,460 citations
- 775UNIV COLUMBIA71 patents · 3,463 citations
- 871CALIFORNIA INST OF TECHN59 patents · 5,567 citations
- 967UNIV NORTHWESTERN26 patents · 4,323 citations
- 1063HOFFMANN LA ROCHE122 patents · 5,479 citations
- 1158UNIV YALE47 patents · 3,371 citations
- 1254GEN PROBE INC46 patents · 4,182 citations
- 1350ILLUMINA CAMBRIDGE LTD59 patents · 2,112 citations
- 1446HOPE CITY29 patents · 2,023 citations
- 1542UNIV TEMPLE16 patents · 4,190 citations
- 1638SCRIPPS RESEARCH INST86 patents · 4,588 citations
- 1733UNIV CALIFORNIA201 patents · 5,915 citations
- 1829UNIV EMORY67 patents · 2,993 citations
- 1925HARVARD COLLEGE84 patents · 2,374 citations
- 2021BECTON DICKINSON CO19 patents · 3,269 citations
- 2117ALNYLAM PHARMACEUTICALS INC71 patents · 1,658 citations
- 2213BRISTOL MYERS SQUIBB CO116 patents · 3,379 citations
- 238REGENERON PHARMA36 patents · 1,205 citations
- 244AGILENT TECHNOLOGIES INC64 patents · 3,942 citations
- 251UNIV PENNSYLVANIA50 patents · 1,353 citations
All-time canon
All-time PatentIndex Score in C07H
- 199AFFYMAX TECH NV22 patents · 19,547 citations
- 296ISIS PHARMACEUTICALS INC452 patents · 67,381 citations
- 392AFFYMETRIX INC128 patents · 27,091 citations
- 488ANTI GENE DEV GROUP7 patents · 11,850 citations
- 583GILEAD SCIENCES INC140 patents · 24,694 citations
- 679UNIVERSITY PATENTS INC17 patents · 11,253 citations
- 775UNIV IOWA RES FOUND53 patents · 8,094 citations
- 871EXIQON AS15 patents · 7,015 citations
- 967CHIRON CORP51 patents · 15,616 citations
- 1063NANOGEN INC40 patents · 7,688 citations
- 1158WORCESTER FOUND EX BIOLOGY12 patents · 5,239 citations
- 1254US HEALTH101 patents · 8,145 citations
- 1350454 LIFE SCIENCES CORP6 patents · 2,521 citations
- 1446UNIV TEXAS102 patents · 6,346 citations
- 1542CENTRE NAT RECH SCIENT38 patents · 5,364 citations
- 1638MAX PLANCK GESELLSCHAFT25 patents · 2,460 citations
- 1733LYNX THERAPEUTICS INC22 patents · 4,844 citations
- 1829UNIV COLUMBIA71 patents · 3,463 citations
- 1925CIBA GEIGY CORP73 patents · 5,785 citations
- 2021RIBOZYME PHARM INC46 patents · 6,337 citations
- 2117SEQUENOM INC18 patents · 4,492 citations
- 2213CALIFORNIA INST OF TECHN59 patents · 5,567 citations
- 238UNIV NORTHWESTERN26 patents · 4,323 citations
- 244HYBRIDON INC45 patents · 5,307 citations
- 251HOFFMANN LA ROCHE122 patents · 5,479 citations
90–99 field-defining50–89 strong<50 emergingearned by citationsfrom family breadth